China Journal of Oral and Maxillofacial Surgery ›› 2019, Vol. 17 ›› Issue (5): 465-468.doi: 10.19438/j.cjoms.2019.05.016

• Clinical Reports • Previous Articles     Next Articles

Recurrent pleomorphic adenoma of the submandibular gland: a clinical and pathologic study of 15 cases

XU Wan-lin1, ZHU Yun1, LU Hao1, LIU Li-min2, SHEN Shu-kun1, LIU Sheng-wen1, YANG Wen-jun1   

  1. 1. Department of Oromaxillofacial Head and Neck Oncology,Shanghai 200011, China;
    2.Department of Oral Pathology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011, China
  • Received:2018-09-12 Online:2019-09-20 Published:2020-03-11

Abstract: PURPOSE: To investigate the clinicopathological feature of recurrent pleomorphic adenoma of the submandibular gland, and discuss its diagnosis, treatment and prognosis. METHODS: From June 2005 to June 2017, the clinical data and pathological features of 15 cases of recurrent pleomorphic adenoma of the submandibular gland treated in Shanghai Ninth People's Hospital were reviewed and analyzed retrospectively. RESULTS: Among 15 cases, 4(26.67%) were male while 11(73.33%) were female. Their age ranged from 25 to 73 years old (mean: 39.33). Three cases (20%) recurred twice and the other 12 patients (80%) recurred once. All patients underwent excision of the mass and submandibular gland (except 2 cases who had undergone excision of the submandibular gland in previous surgery), and the pathological results were recurrent pleomorphic adenoma, with multi-nodules and incomplete capsule. The follow-up period was 1-13 years (median: 6) and only 1 patient (6.67%) suffered from suspected recurrence, who didn't receive second surgery due to his old age. CONCLUSIONS: Recurrent pleomorphic adenoma in the submandibular gland is rare. Its clinical and pathological features were similar to those of the primary pleomorphic adenoma and surgical treatment is effective.

Key words: Recurrent pleomorphic adenoma, Submandibular gland, Salivary gland

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