China Journal of Oral and Maxillofacial Surgery ›› 2015, Vol. 13 ›› Issue (3): 270-272.

• Review Articles • Previous Articles     Next Articles

Research progress on lymphoepithelial carcinoma of salivary gland

TAN Yi-ran, ZHONG Lai-ping   

  1. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China
  • Received:2014-01-08 Revised:2014-11-24 Online:2015-05-20 Published:2015-06-18

Abstract: Lymphoepithelial carcinoma of salivary gland is a rare primary carcinoma in salivary gland. It was first described by Hilderman in 1962. It had different designation in the literatures as lymphoepithelioma-like carcinoma, malignant lymphoepithelial lesion, undifferentiated carcinoma with lymphoid stroma, carcinoma in lymphoepithelial lesion. It was finally defined as lymphoepithelial carcinoma in histological classification of salivary gland tumors (version 3 of pathology and genetics of head and neck tumors in World Health Organization classification of tumors in 2005). There is still no standard treatment guideline for lymphoepithelial carcinoma of salivary gland, the paper briefly reviewed current progress on lymphoepithelial carcinoma of salivary gland on the aspects of carcinogenesis, clinical and pathological features, diagnosis, treatment and prognosis to improve the comprehensive understanding of this disease.

Key words: Salivary gland, Lymphoepithelial carcinoma, Epstein-Barr virus

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