Prognosis of adenoid cystic carcinoma in head and neck region: a single-centre experience

doi:10.19438/j.cjoms.2023.05.007

Abstract

Abstract: PURPOSE: To explore the prognostic factors of adenoid cystic carcinoma (ACC) in head and neck region by analyzing associated clinical characters. METHODS: A total of 188 patients with ACC in head and neck region were enrolled, and the follow-up was carried out by outpatient review or telephone. Kaplan-Meier method was used to assess the survival rates, and Cox regression analysis was used to identify the associated prognostic factors with SPSS 26.0 software package. RESULTS: The overall survival rate of 188 patients was 76.6%, of which 13.3% died of recurrence and 10.1% died of distant metastasis. The rate of local recurrence and distant metastasis were 23.9% and 10.1%, of which the survival rate was 42.2% and 68.4%, respectively. Cox regression analysis revealed that age, T stage, N stage, and regimens were significantly associated with survival of ACC. CONCLUSIONS: In ACC, age, T stage, N stage, and regimen were independent prognostic factors of survival, age and nerve invasion were independent prognostic factors of recurrence, and N stage was independent prognostic factor of distant metastasis.

Key words: Adenoid cystic carcinoma, Head and neck region, Prognosis analysis

CLC Number:

R739.8

CHENG Yu-tian, XU Le, MA Li, WU Hai-wei, CHEN Zhan-wei, ZOU Hu-wei, ZHANG Tian-qi, LIU Gui-jun, LIU Zhen-xing, YIN Chang-wei, LI Wen-gang, ZHANG Shi-zhou, HUANG Sheng-yun, ZHANG Dong-sheng. Prognosis of adenoid cystic carcinoma in head and neck region: a single-centre experience[J]. China Journal of Oral and Maxillofacial Surgery, 2023, 21(5): 467-471.

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