Abstract: PURPOSE: To analyze the difference between oral and maxillofacial space infection(OMSI) patients with diabetes mellitus, stress hyperglycemia and normal blood glucose in general data, clinical manifestations, laboratory test, and dominant bacterial flora of infection. METHODS: A retrospective study was conducted in 190 patients diagnosed with oral and maxillofacial infection and treated at the Department of Oral Surgery, Shanghai Ninth People's Hospital from August 2020 to June 2022. Statistical analysis of general data, clinical manifestations, laboratory test, and dominant bacterial flora of infection between the three groups was performed with SPSS 25.0 software package. RESULTS: Between diabetic group and stress hyperglycemia group, absolute number of lymphocytes, sodium and chlorine differed significantly; between diabetic group and normal blood glucose group, age, neutrophil absolute number, neutrophil percentage, lymphocyte percentage, C-reactive protein, IL-6, IL-8, tumor necrosis factor-α, procalcitonin, urea, serum uric acid, fibrinogen, sodium, chlorine and total carbon dioxide differed significantly; between stress hyperglycemia group and normal glycemia group,the percentage of neutrophil, percentage of lymphocyte, absolute number of lymphocyte, C-reactive protein, IL-8, tumor necrosis factor-α, and urea differed significantly. CONCLUSIONS: The clinical features and laboratory results of OMSI patients with diabetes, stress hyperglycemia and normal blood glucose are significantly different, suggesting that the three groups of patients should be distinguished in clinical diagnosis and treatment, and more targeted treatment should be provided.

Key words: Oral and maxillofacial region, Space infection, Diabetes mellitus, Stress hyperglycemia