China Journal of Oral and Maxillofacial Surgery ›› 2020, Vol. 18 ›› Issue (6): 563-566.doi: 10.19438/j.cjoms.2020.06.018

• Review Articles • Previous Articles     Next Articles

Progress on interleukin-8 in epithelial-mesenchymal transition of oral squamous cell carcinoma

XU Qiao-shi, YANG Xi, MA Hai-long, CHANG Han-yue, ZHANG Chen-ping   

  1. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011, China
  • Received:2019-07-24 Revised:2020-01-09 Published:2020-12-31

Abstract: Interleukin-8 IL-8 is a chemokine belonging to CXC subgroup, it plays a critical role in tumor progress as well as attracting immune cell. In this review, we descripted the biological characteristics of IL-8, analyzed its promoting function for epithelial-mesenchymal transition in oral squamous cell carcinoma, and summarized the progress of current studies. Based on the results of existing researches, the outlook for future study about IL-8 was proposed. ;

Key words: Interleukin 8, Oral squamous cell carcinoma, Epithelial-mesenchymal transition

CLC Number: