China Journal of Oral and Maxillofacial Surgery ›› 2020, Vol. 18 ›› Issue (4): 375-380.doi: 10.19438/j.cjoms.2020.04.018

• Review Articles • Previous Articles     Next Articles

Progress in topical of application β-blockers in the treatment of infantile hemangioma

GU Da1, HUO Ran2, XU Guang-qi2, BI Jian-hai2, LI Shang-bin2   

  1. 1. Department of Plastic Surgery, Jinan Central Hospital Affiliated to Shandong First Medical University. Jinan 250000, Shandong Province;
    2. Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University. Jinan 250000, Shandong Province, China
  • Received:2019-03-06 Online:2020-07-20 Published:2020-09-10

Abstract: Hemangioma is the most common benign tumor in infants and young children. It is mainly treated by topical and systemic medication, supplemented by laser therapy, depending on the location, size, extent, depth, stage, functional and psychological impact on children. Oral propranolol is currently the first-line treatment for superficial hemangioma. However, topical β-blockers are more likely to be accepted by children's parents, and their use is gradually increasing. This article reviewed the research progress of β-blockers in the treatment of infantile hemangiomas in recent years, with the aim to provide a theoretical basis for the treatment of infantile hemangiomas.

Key words: Infantile hemangioma, Superficial, Propranolol, Timolol, Topical application

CLC Number: