Clinical study of oral squamous cell carcinoma with clinically negative cervical lymph node in 111 consecutive case

doi:10.19438/j.cjoms.2019.04.016

Abstract

Abstract: PURPOSE: To investigate some clinical and pathological factors influencing metastasis in oral squamous cell carcinoma(OSCC) patients with clinically negative cervical lymph nodes(cN0). METHORDS: The clinical and pathologic data of 111 OSCC patients with clinically negative cervical lymph nodes between 2007.5-2017.5 were investigated retrospectively. The data were analyzed using SPSS 17.0 software package. Results: The total occult metastasis rate was 27.03%(30/111) in 111 cN0 patients with OSCC. Patient's gender, age, primary site had no significant impact on metastasis (P>0.05), while histopathologic grade of the diseases was closely related to cervical lymph node metastasis. Conclusions: The greater of tumor volume, the lower the degree of differentiation, the smaller the age, the higher occult lymph node metastasis rate. It is suggested that cN0 OSCC patients should be treated with selective neck dissection.

Key words: Oral squamous cell carcinoma, Occult cervical lymph node metastasis, Neck dissection

CLC Number:

R739.8

HAN Shang-zhi, LV Xin, CHEN Xi-bo, LI Le, HAO Li-li, ZHANG Xing-le. Clinical study of oral squamous cell carcinoma with clinically negative cervical lymph node in 111 consecutive case[J]. China Journal of Oral and Maxillofacial Surgery, 2019, 17(4): 356-358.

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