Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

China Journal of Oral and Maxillofacial Surgery ›› 2015, Vol. 13 ›› Issue (2): 117-123.

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Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

TIAN Hai-suo^{1, 2}, LIN Dong-peng¹, ZHAO Tian-yi¹, YU Bo¹, MA Qin¹

1.State Key Laboratory of Military Stomatology, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Forth Military Medical University. Xi'an 710032, Shaanxi Province;
2. Department of Stomatology, Armed Police Corps Hospital in Liaoning Province. Shenyang 110034, Liaoning Province, China

Received:2014-09-25 Revised:2014-11-27 Online:2015-03-20 Published:2015-04-23
Supported by:
Supported by Science and Technology Research Planning Project of Shaanxi Province (2012SF2-20-2)

Abstract

Abstract: PURPOSE: Histological changes were studied to evaluate the effect of fractional Er:YAG laser treatment on oral mucosa tissues. METHODS: The rabbit oral mucosa was irradiated with Er:YAG laser. The epithelial thickness, lamina propria collagen fiber and elastic fiber content were assessed at 1, 2, 4 weeks after OP. H-E staining, Masson staining and elastic fiber staining were utilized. The experimental results were statistically analyzed by SPSS19.0 software package. RESULTS: After dot matrix Er:YAG irradiation, mucosal damage zone was limited only within the mucosal epithelium, and healed completely in 3-7 days, without leaving scar and pigment. The epithelial thickness was increased significantly (P<0.05), and the lamina propria collagen fiber and elastic fiber content were increased significantly (P< 0.05). After fractional Er:YAG laser irradiation, the rabbit had a small oral mucosa lesion and healed quickly. The epithelial remodeled. The mucosa lamina propria collagen contracted. CONCLUSIONS: After fractional Er:YAG laser irradiation, collagen fiber and elastic fiber proliferated and remodeled. The mucosa was tightening and the mucous membrane elasticity was increased.

Key words: Er:YAG Laser, Collagen fiber, Elastic fiber, Rabbit

CLC Number:

R782.2

TIAN Hai-suo, LIN Dong-peng, ZHAO Tian-yi, YU Bo, MA Qin. Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation[J]. China Journal of Oral and Maxillofacial Surgery, 2015, 13(2): 117-123.

References

[1] 叶京英, 王小轶, 韩德民, 等. 中老年女性阻塞性睡眠呼吸暂停低通气综合征的社区调查 [J]. 中华耳鼻咽喉头颈外科杂志, 2005, 40(8): 611-617.
[2] 王桂清, 孙宝君. 阻塞性睡眠呼吸暂停低通气综合征 [J]. 人民军医, 2007, 50(4): 235-238.
[3] Jovanovic J. Laser-assisted snoring and apnea reduction, 9 months of experience (summary) [J]. J Laser Health Acad, 2011, 5(Suppl 1):S11.
[4] Dovsak D, Gabrijelcic J, Vizintin Z. A new laser treatment method for the reduction of snoring and sleep apnea a pilot study (summary) [J]. J Laser Health Acad, 2011, 5(Suppl 1): S9-10.
[5] Verse T. Update on surgery for obstructive sleep apnea syndrome[J]. HNO,2008,56(11): 1098-1104.
[6] Li HY, Lee LA. Relocation pharyngoplasty for obstructive sleep apnea [J]. Laryngoscope, 2009,119(12): 2472-2477.
[7] Shin SH, Ye MK, Kim CG. Modified uvulopalatopharyngoplasty for the treatment of obstructive sleep apnea-hypopnea syndrome: resection of the musculus uvulae [J]. Otolaryngol Head Neck Surg,2009,140(6): 924-929.
[8] Miracki K, Vizintin Z. Nonsurgical minimally invasive Er:YAG laser snoring treatment[J]. J Laser Health Acad,2013,7(1):36-41.
[9] Svahnström K. Er:YAG laser treatment of sleep-disordered breathing[J]. J Laser Health Acad,2013, 7(2): 13-16.
[10] Manstein D, Herron GS, Sink RK, et a1. Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury [J]. Lasers Surg Med, 2004, 34(5): 426-438.
[11] 刘科峰, 王艳君, 吴玉强. 调Q开关Nd：YAG激光治疗色素性皮肤病403例 [J]. 皮肤病与性病, 2005, 27(3): 39-40.
[12] 周国瑜. 点阵激光治疗技术的发展和应用概述 [J]. 皮肤性病诊疗学杂志, 2011, 18(2): 71-72.
[13] 邬宗周, 袁定芬, 章伟, 等. 点阵Er：YAG激光对光老化豚鼠皮肤胶原纤维的影响 [J]. 中国皮肤科杂志, 2013, 46(9): 648-651.
[14] Lee JY,Kim YK,Seo JY,et a1.Loss of elastic fibers causes skin wrinkles in sun-damaged human skin[J]. J Dermatol Sci,2008,50(2):99-107.

Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

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