CT and MR imaging features of peripheral keratocystic odontogenic tumors

Abstract

Abstract: PURPOSE: Peripheral keratocystic odontogenic tumor (PKCOT) is a rare entity and the imaging findings have not been reported. The aim of this study was to explore CT and MR imaging characteristics of two PKCOTs in lateral facial deep region (LFDR), and review their clinical and radiological characteristics. METHODS: Nineteen PKCOTs were found, including seventeen from the literatures and two new cases reported in the present study. Sixteen of them were located in the gingiva, one in the buccal space and two in LFDR. CT imaging features were based on one PKCOT in the buccal space and two in LFDR. MR imaging features were detected on one PKCOT in LFDR, and conventional radiographic characteristics were determined on nine PKCOTs. RESULTS: The patients aged from 37 to 83 years, with a mean age of 56.5 years. The male to female ratio was 1:1.285, with no predilection for either gender. Buccal space(5.2%) and LFDR (10.5%) were relatively rare original sites for PKCOTs, compared with gingiva (84.2%). PKCOTs were clearly depicted on CT and MR imaging as they had cystic changes. Contents of the cysts were further analyzed by using different series of MRI. No radiological features were found on radiographs except one with minimal bone resorption in the alveolar crest. CONCLUSIONS: LFDR is a rare original site for PKCOT. PKCOT should be included as one of differential diagnosis of cystic lesions found in LFDR on CT and MR imaging.

Key words: Peripheral keratocystic odontogenic tumor, Lateral deep facial region, CT, MRI

CLC Number:

R739.8

ZHU Ling, ZHENG Jia-wei, YANG Jie. CT and MR imaging features of peripheral keratocystic odontogenic tumors[J]. China Journal of Oral and Maxillofacial Surgery, 2014, 12(2): 167-171.

References

[1] Eryilmaz T, Ozmen S, Findikcioglu K, et al. Odontogenic keratocyst: an unusual location and review of the literature [J]. Ann Plast Surg, 2009, 62(2): 210-212.
[2] Madras J, Lapointe H. Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour[J]. J Can Dent Assoc, 2008, 74(2): 165-165.
[3] Pindborg JJ, Philipsen HP, Henriksen J. Studies on odontogenic cyst epithelium[C]//Sognnaes RF. Fundamentals of keratinization [M]. Washington(DC): American Association for the Advancement of Science, 1962: 151-160.
[4] Kleihues P, Sobin LH. Odontogenic tumours [C]//Barnes L, Eveson JW, Reichart PA, et al. World Health Organization classification of tumours: pathology and genetics of tumours of the head and neck [M]. Lyon: IARC Press, 2005: 284-328.
[5] Gröbe A, Hanken H, Blessmann M, et al. An odontogenic keratocystic tumor in the buccal space: an unusual site of origin and a review of the literature [J]. In Vivo , 2012, 26(5): 847-851.
[6] Dayan D,Buchner A, Gorsky M, et al. The peripheral odontogenic keratocyst[J]. Int J Oral Maxillofac Surg,1988,17(2): 81-83.
[7] Ide F, Shimoyama T, Horie N. Peripheral odontogenic keratocyst: a report of 2 cases [J]. J Periodontol, 2002, 73(9): 1079-1081.
[8] Chi AC, Owings JR Jr, Muller S. Peripheral odontogenic keratocyst: report of two cases and review of the literature [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005, 99(1): 71-78.
[9] Chehade A, Daley TD, Wysocki GP, et al. Peripheral odontogenic keratocyst[J]. Oral Surg Oral Med Oral Pathol,1994,77(5):494-497.
[10] Vij H, Vij R, Gupta V, et al. Odontogenic keratocyst: a peripheral variant [J]. Niger J Clin Pract, 2011, 14(4): 504-507.
[11] Preston RD, Narayana N. Peripheral odontogenic keratocyst[J]. J Periodontol, 2005, 76(12): 2312-2315.
[12] Faustino SE, Pereira MC, Rossetto AC, et al. Recurrent peripheral odontogenic keratocyst: a case report[J]. Dentomaxillofac Radiol, 2008, 37(7): 412-414.
[13] Stoelinga PJ, Cohen MM Jr, Morgan AF. The origin of keratocysts in the basal cell nevus syndrome[J]. J Oral Surg,1975,33(9):659-663.
[14] Buchner A, Hansen LS. The histomorphologic spectrum of the gingival cyst in the adult [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1979, 48(6): 532-539.
[15] Ide F, Saito I. Many faces of odontogenic keratocyst [J]. Oral Oncol, 2003, 39(2): 204-205.
[16] Wang J, Takashima S, Takayama F, et al. Head and neck lesion: characterization with diffusion-weighted echo-planar MR imaging[J]. Radiology, 2001, 220(3): 621-630.
[17] Curé JK. Imaging of vascular lesions of the head and neck [J]. Facial Plast Surg Clin North Am, 2001, 9(4): 525-549.
[18] Vilanova JC, Barcel&#x0dbc0;&#x0dda9; J, Villal&#x0dbc0;&#x0dda9;n M. MR and MR angiography characterization of soft tissue vascular malformations [J]. Curr Probl Diagn Radiol, 2004, 33(4): 161-170.
[19] Shah GV. MR imaging of salivary glands [J]. Neuroimaging Clin N Am, 2004, 14(4): 777-808.
[20] Asaumi J, Shigehara H, Konouchi H, et al. Assessment of carcinoma in the sublingual region based on magnetic resonance imaging [J]. Oncol Rep, 2002, 9(6): 1283-1287.