Abstract: PURPOSE: To investigate the influencing factors of tracheal extubation time after general anesthesia in children with obstructive sleep apnea syndrome(OSAS) who underwent palatopharyngoplasty, tonsillectomy and/or adenoidectomy (ablation). METHODS: A total of 529 children (ASA gradeⅠ-Ⅱ, aged 3-12 years) with OSAS who underwent palatopharyngoplasty/tonsillectomy and/or adenoidectomy(ablation) under general anesthesia were retrospectively analyzed. In the data collected, the first 75% of the quartile was defined as "fast extubation" and the remaining 25% was defined as "slow extubation" in order of extubation time from fast to slow. There were 137 cases with slow extubation after anesthesia, and 392 cases with rapid extubation after anesthesia. The data of the two groups were compared, and the influencing factors of extubation time were analyzed by stepwise regression with SPSS 21.0 software package. RESULTS: There were significant differences between the two groups in emergence agitation, anesthesia method (inhalation anesthesia vs intravenous anesthesia), total amount of fentanyl, use of dexmedetomidine and neostigmine, and use of analgesic pump (P<0.05). CONCLUSIONS: Emergence agitation, anesthesia method, total amount of fentanyl, use of dexmedetomidine and neostigmine, and use of analgesic pump were the influencing factors of tracheal extubation time.

Key words: Extubation time, General anesthesia, Obstructive sleep apnea syndrome, Children