Clinical study of platelet- rich fibrin (PRF) combined autogenous bone in auto-dental immediate transplantation

Abstract

Abstract: PURPOSE: To investigate the clinical feasibility of application of platelet-rich fibrin(PRF) combined with autogenous bone grafting in the treatment of periodontal bone defect with immediate autogenous tooth transplantation. METHODS: From January 2014 to December 2015, 130 cases of immediate autogenous tooth transplantation were randomly divided into group A, B and C according to the wishes of patients and the order of treatment. Different graft materials were filled in the bone defect. In group A, 60 patients were treated with PRF combined with autogenous bone implantation; In group B, 35 patients were implanted with PRF alone. In group C, 35 patients were treated with autogenous bone graft. The patients were followed up for 12 months, the degree of teeth loosening and imaging films after operation were taken and evaluated. SPSS 13.0 software package was used for statistical analysis. RESULTS: In group A, the success rate was 80% and the effective rate was 96.4%; In group B, the success rate was 51.4%, the effective rate was 80%; In group C, the success rate was 57.1%, the effective rate was 77.1%. χ² test showed significant difference in success rate effective rate between group A and group B, group A and group C (P<0.05), but no significant difference between group B and group C (P>0.05). CONCLUSIONS: Placement of PRF combined with autogenous bone can promote periodontal osteogenesis, which is beneficial to the stability of transplanted teeth.

Key words: Platelet-rich fibrin, PRF, Immediate transplantation, Bone defect, Autogenous teeth

CLC Number:

R782.12

LIU Jun-ping, CHEN Fu-guang, KUANG Jian-pin. Clinical study of platelet- rich fibrin (PRF) combined autogenous bone in auto-dental immediate transplantation[J]. China Journal of Oral and Maxillofacial Surgery, 2016, 14(6): 527-531.

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