Effect of A-PRF membrane on promoting regeneration of attached gingival around dental implants

doi:10.19438/j.cjoms.2019.02.009

Abstract

Abstract: PURPOSE: Advanced platelet-rich fibrin(A-PRF) was applied in vestibular extension surgery to explore its effect on promoting regeneration of attached gingival around dental implants. METHODS: Twenty-six patients with insufficient attached gingiva around dental implants were enrolled in this study from October 2015 to July 2017, they were randomly divided into two groups(n=13). The experimental group received vestibular extension surgery with A-PRF membrane covering the wound, while the control group only received routine surgery. Increase of attached gingival, mucosa healing status and pain intensity were evaluated at different time points after surgery. SPSS 17.0 software package was used for statistical analysis. RESULTS: In the experimental group, increase of attached gingival at 2 and 12 weeks was (3.15±0.36) mm and (2.81±0.36) mm respectively, which was significantly higher than those [(2.93±0.29) mm and (2.52±0.30) mm] in the control group (P<0.05). The mucosa healing status in the experimental group at 2 and 12 weeks was also significantly better than that in the control group (P<0.05). Visual analogue scale (VAS) of pain in the experimental group was 51.03±12.20, which was significantly lower than that (58.22±9.86) in the control group (P<0.05). CONCLUSIONS: Application of A-PRF membrane in vestibular extension surgery could effectively promote mucosa healing, relieve postoperative pain and increase attached gingival regeneration around dental implants.

Key words: Advanced platelet-rich fibrin, Attached gingival, Dental implants, Peri-implantitis, Vestibular extension surgery

CLC Number:

R782.1

MA Xiao-yu, FENG Xiao-jie, QI Meng-chun, WANG Yi-rui, DONG Wei, DU Shuo. Effect of A-PRF membrane on promoting regeneration of attached gingival around dental implants[J]. China Journal of Oral and Maxillofacial Surgery, 2019, 17(2): 146-149.

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