Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review

China Journal of Oral and Maxillofacial Surgery ›› 2015, Vol. 13 ›› Issue (2): 190-192.

• Case Reports • Previous Articles

Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review

XU Yi-na, YANG Zhao-hui, ZHANG Da-ming, WANG You-yuan, CHEN Wei-liang

Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Guangzhou 510120, Guangdong Province, China

Received:2014-01-17 Revised:2014-03-24 Online:2015-03-20 Published:2015-04-23

Abstract

Abstract: To analyze the therapeutic effect of patient suffering from hyalinizing clear cell carcinoma of the soft palate and review of the related literatures. An 18-year-old female patient with a mass on the soft palate was surgically treated in our department. The postoperative pathologic diagnosis was hyalinizing clear cell carcinoma. Glandular hyalinizing clear cell carcinoma is a rare low-grade malignancy without obvious symptoms, usually confirmed by pathology and assisted by immunohistochemistry. Clinically and histopathologically, hyalinizing clear cell carcinoma needs to be differentiated from other malignancies including clear cells such as mucoepidermoid carcinomas et al. It is treated by wide surgical excision and has better prognosis than other salivary gland cancers.

Key words: Clear cell carcinoma, Soft palate, Pathology

CLC Number:

R739.8

XU Yi-na, YANG Zhao-hui, ZHANG Da-ming, WANG You-yuan, CHEN Wei-liang. Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review[J]. China Journal of Oral and Maxillofacial Surgery, 2015, 13(2): 190-192.

References

[1] Milchgrub S, Gnepp DR, Vuitch F, et al. Hyalinizing clear cell carcinoma of salivary gland[J]. Am J Surg Pathol, 1994, 18(1): 74-82.
[2] Ellis GL, Auclair PL. Tumors of the salivary glands [M]. Washington: American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, 1996: 281-289.
[3] Barnes L, Eveson JW, Reichart P, et al. World Health Organization classification of tumours: pathology and genetics of head and neck tumours [M]. 3rd ed. Lyon: IARC Press, 2005: 227 -228.
[4] Testa D, Galli V, de Rosa G, et al. Clinical and prognostic aspects of laryngeal clear cell carcinoma[J]. J Laryngol Otol, 2005, 119(12): 991-994.
[5] Balakrishnan R, Nayak DR, Pillai S, et al. Hyalinizing clear cell carcinoma of the base of the tongue[J]. J Laryngol Otol, 2002, 116(10): 851-853.
[6] Adil E, Setabutr D, Mikesell K, et al. Hyalinizing clear cell adenocarcinoma of the oropharynx[J]. Head Neck, 2013, 35(6): E184-186.
[7] 王强, 沈毅, 孙坚. 唾液腺透明细胞癌的诊断与治疗[J]. 中国口腔颌面外科杂志, 2008, 6(4): 266-269.
[8] Weinreb I. Hyalinizing clear cell carcinoma of salivary gland: a review and update[J]. Head Neck Pathol,2013,7(Suppl 1):S20-29.
[9] Saleh KA,Nurishmah MI,Firouzeh GN,et al.Primary clear cell carcinoma of minor salivary gland of the soft palate: a case report[J]. Med J Malaysia, 2012, 67(3): 335-336.
[10] Pujary K, Rangarajan S, Nayak DR, et al. Hyalinizing clear cell carcinoma of the base of tongue[J]. Int J Oral Maxillofac Surg, 2008, 37(1): 93-96.
[11] Gon S, Bhattacharyya A, Majumdar B, et al. Post-radiotherapy locoregional recurrence of hyalinizing clear cell carcinoma of palate [J]. J Cancer Res Ther, 2013, 9(2): 281-283.
[12] Solar AA, Schmidt BL, Jordan RC. Hyalinizing clear cell carcinoma:case series and comprehensive review of the literature[J]. Cancer, 2009, 115(1): 75-83.

Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 4

Recommended Articles

Metrics

Comments

[1]	XU Gang, SONG Qi-yi, JIANG Wei-dong, LIU Jing-xiu. Expression and clinical significance of aquaporin 3 in oral mucosal epithelial dysplasia and oral squamous cell carcinoma [J]. China Journal of Oral and Maxillofacial Surgery, 2022, 20(5): 478-482.
[2]	YANG Yang, PANG Chao-yuan, ZHANG Wen-kai, MA Dong-yang. Mandibular mass as the initial presentation of renal clear cell carcinoma: report of two cases and literature review [J]. China Journal of Oral and Maxillofacial Surgery, 2020, 18(1): 87-90.
[3]	CHEN Jia, ZHOU Jie, WANG Guo-dong, HUANG Jian-tao, CHEN Xiao-qing, WU Yang, LIU Yuan, JIANG Lei, ZHAO Yun-fu. Castleman’s disease of the head and neck: a clinicopathologic study of 10 cases [J]. China Journal of Oral and Maxillofacial Surgery, 2016, 14(3): 257-262.
[4]	YANG Yang, JIANG Li-ping, LIU Qiong, WANG Guo-min. The current status of speech therapy for cleft patients in 42 medical institutions in China [J]. China Journal of Oral and Maxillofacial Surgery, 2014, 12(1): 25-29.