Reconstruction of minor defect after resection of tongue squamous cell carcinoma with improved C-type heterogenic acellular dermis matrix

Abstract

Abstract: PURPOSE: To study the clinical value of reconstruction of minor defect after resection of tongue squamous cell carcinoma which was smaller than 25 mm×25 mm and only involved submucosa or superficial muscle with improved C-type heterogenic acellular dermis matrix. METHODS: Sixty-four cases were selected which underwent improved C-type heterogenic acellular dermis matrix (H-ADM) to reconstruct minor defect after resection of tongue squamous cell carcinoma. All wound surfaces were packaged and fixed with H-ADM. Changes of epithelium converting into mucosa was observed when the package was removed and 1, 2, 7, 14, 28 days, 3, 6, 12 months after surgery. RESULTS: All patients were followed up. Wound surface recovered well, and the most important feature was the para-mucus pseudomembrane after H-ADM degraded. The para-mucus pseudomembrane reached peak at 1-week, then descended gradually and disappeared 2 months later. Wound surface was then covered with indefinite, slightly atrophied and smooth tissues. CONCLUSIONS: H-ADM can obviously promote wound healing after resection of tongue squamous cell cancer; pressure dressing with vaseline indoform gauze also play an important role in wound healing promotion; H-ADM has satisfactory biocompatibility.

Key words: Heterogenic acellular dermis matrix, Reconstruction, Tongue squamous cell carcinoma

ZHOU Yu, YE Mao-chang, LI Rong-xin, WANG Lai-ping.. Reconstruction of minor defect after resection of tongue squamous cell carcinoma with improved C-type heterogenic acellular dermis matrix[J]. China Journal of Oral and Maxillofacial Surgery, 2014, 12(1): 56-60.

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