Chinese expert consensus on prevention and management of perioperative venous thromboembolism in head and neck cancer patients

doi:10.19438/j.cjoms.2024.01.001

China Journal of Oral and Maxillofacial Surgery ›› 2024, Vol. 22 ›› Issue (1): 1-9.doi: 10.19438/j.cjoms.2024.01.001

• Expert Consensus • Previous Articles Next Articles

Chinese expert consensus on prevention and management of perioperative venous thromboembolism in head and neck cancer patients

REN Zhen-hu¹, CHEN Ming-tao¹, WU Han-jiang², ZHANG Sheng², FANG Kun³, XIE Shang⁴, LIU Yu⁵, HU Chuan-yu⁶, LIU Bing⁷, LI Chun-Jie⁸, ZHU Gui-quan⁸, WANG Cheng⁹, GAO Yang¹⁰, ZHANG Xiao-chen¹, SHI Jian-bo¹, ZHANG Yong-hong¹¹, CUI Ming-zhe¹², JI Tong¹³, REN Guo-xin¹, WANG Yan-an¹, CHEN Wei-liang¹⁴, ZHANG Chen-ping¹, HE Yue¹, ZHANG Zhi-yuan¹

1.Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology. Shanghai 200011;
2. Department of Oral and Maxillofacial Surgery, Second Xiangya Hospital, Central South University. Changsha 410011, Hunan Province;
3. National Center for Cardiovascular Disease; Department of Vascular Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences. Beijing 100037;
4. National Center for Stomatology; National Clinical Research Center for Oral Diseases; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology. Beijing 100081;
5. Department of Oral and Maxillofacial Surgery, School of Stomatology, Zhejiang University. Hangzhou 310020, Zhejiang Province;
6. Department of Oral and Maxillofacial Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. Wuhan 430030, Hubei Province;
7. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University. Wuhan 430070, Hubei Province;
8. National Center for Stomatology; National Clinical Research Center for Oral Diseases; State Key Laboratory of Oral Diseases; Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University. Chengdu 610041, Sichuan Province;
9. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Sun Yat-sen University. Guangzhou 510055, Guangdong Province;
10. Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Soochow University. Suzhou 215000, Jiangsu Province;
11. Department of Oral and Maxillofacial Surgery, Huaihe Hospital of Henan University. Kaifeng 475000, Henan Province;
12. Department of Vascular Surgery, Henan Provincial People’s Hospital. Zhengzhou 450000, Henan Province;
13. Department of Oral and Maxillofacial Surgery, Zhongshan Hospital, Fudan University. Shanghai 200032;
14. Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital,Sun Yat-sen University. Guangzhou 510120,Guangdong Province, China

Received:2023-10-29 Revised:2023-11-15 Online:2024-01-20 Published:2024-02-05

Abstract

Abstract: Venous thromboembolism (VTE) is a common complication after surgical procedures, and an important risk factor for unexpected death in hospitals, and the second leading cause of death for tumor patients. Patients with advanced head and neck cancer usually require extensive radical surgery and simultaneous repair and reconstruction surgery, and have many risk factors such as elderly, long surgical time, long postoperative bed rest, and hypercoagulable state caused by tumor and chemotherapy drugs, which suggest that patients with head and neck cancer should be an extremely high risk group for VTE. However, little attention has been paid to the occurrence of VTE in patients with cancer in the head and neck, and the data on the incidence of VTE after head and neck cancer surgery are also limited. So far, there is a lack of relevant treatment consensus or guidelines for perioperative VTE of head and neck cancer in China. The level of prevention and management of perioperative VTE of head and neck cancer varies among different institutions, and there is a lack of unified and scientific diagnosis and treatment standards and objective evaluation system for prevention and management. In order to unify and standardize the diagnosis and treatment of perioperative VTE in head and neck cancer, reduce the waste of medical resources and improve the treatment effectiveness, domestic experts in this field have repeatedly discussed the diagnosis and treatment opinions from 14 famous medical institutions in China. This article refers to the research results and diagnosis and treatment experience of perioperative VTE in head and neck cancer world wide in recent years, and formulates this expert consensus for reference by relevant clinicians.

Key words: Venous thromboembolism, Pulmonary embolism, Head and neck tumor, Expert consensus

CLC Number:

R739.8

REN Zhen-hu, CHEN Ming-tao, WU Han-jiang, ZHANG Sheng, FANG Kun, XIE Shang4, LIU Yu, HU Chuan-yu6, LIU Bing, LI Chun-Jie, ZHU Gui-quan, WANG Cheng, GAO Yang, ZHANG Xiao-chen, SHI Jian-bo, ZHANG Yong-hong, CUI Ming-zhe, JI Tong, REN Guo-xin, WANG Yan-an, CHEN Wei-liang, ZHANG Chen-ping, HE Yue, ZHANG Zhi-yuan. Chinese expert consensus on prevention and management of perioperative venous thromboembolism in head and neck cancer patients[J]. China Journal of Oral and Maxillofacial Surgery, 2024, 22(1): 1-9.

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Chinese expert consensus on prevention and management of perioperative venous thromboembolism in head and neck cancer patients

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