Accuracy of detachable 3D-printed stent placement in radiotherapy for oral cancer patients

doi:10.19438/j.cjoms.2022.05.009

Abstract

Abstract: PURPOSE: To customize a detachable 3D-printed oral stent for patients with oral cancer radiotherapy, the stent was connected with thermoplastic film to improve the positioning accuracy of patients. METHODS: Twenty patients with oral cancer were randomly divided into control group and experimental groups, patients in the experimental group used detachable 3D-printed stents placement while patients in the control group used traditional 3D-printed oral stents. X1, Y1, Z1 direction of translation and X2, Y2, Z2 direction of rotating beam position error were obtained by cone-beam CT (CBCT) in patients before (1st radiotherapy), during (10th radiotherapy), and after radiotherapy (20th radiotherapy). The positioning errors of the third cervical spine and the horizontal ramus of the mandible were evaluated for clinical positioning errors. SPSS 23.0 software package was used for data analysis. RESULTS: The mean translational errors in X1, Y1 and Z1 directions were (0.120±0.083), (0.180±0.250), (0.170±0.150) cm in the control group, and (0.081±0.084), (0.047±0.059) , (0.046±0.036) cm in the experimental group. The difference was statistically significant in the Y1(t=2.4, P<0.05) and Z1(t=3.64, P<0.05) direction. The mean rotational positioning errors of X2, Y2 and Z2 were 1.04°±0.62°, 1.26°±1.30°, 0.65°±0.55° in the control group and 0.67°±0.73°, 0.54°±0.24°, 0.45°±0.37° in the experimental group. The difference was statistically significant in the direction of Y2(t=2.53, P<0.05). The displacement of the third cervical vertebra in the control group and the experimental group was (0.130±0.080) and (0.074±0.090) cm. The displacement at the end point of the horizontal ramus of the mandible was (0.240±0.180) cm in the control group and (0.095±0.065) cm in the experimental group, which had significant difference (t=2.99, P<0.05). CONCLUSIONS: Compared with traditional 3D printed oral stent, the detachable 3D printed oral stent can effectively improve the positioning accuracy and has a good clinical application prospect.

Key words: 3D-printing, Separable type, Fixed thermoplastic film, Position error, Oral cancer, Radiation therapy

CLC Number:

R730.55

FAN Wen-hui, LAO Zheng, SHI Hui-feng, BI Fan, TU Wen-yong, HU Hai-sheng. Accuracy of detachable 3D-printed stent placement in radiotherapy for oral cancer patients[J]. China Journal of Oral and Maxillofacial Surgery, 2022, 20(5): 466-470.

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