Changes of cerebral frontal and temporal lobes after trigeminal ganglion radiofrequency thermocoagulation

doi:10.19438/j.cjoms.2020.04.006

Abstract

Abstract: PURPOSE: To explore the clinical effects of CT-guided trigeminal ganglion percutaneous radiofrequency thermocoagulation (PRT) on idiopathic trigeminal neuralgia (ITN) and patients' brain function changes. METHODS: Seventeen patients with ITN admitted to the Affiliated Stomatology Hospital of Anhui Medical University and the First Affiliated Hospital of Anhui Medical University were selected as study subjects. Brain function was detected by functional magnetic resonance imaging(fMRI) before and after CT-guided PRT surgery. SPSS 16.0 software was used to compare the changes in low-frequency amplitude (f-ALFF) value, pain condition (VAS score), adverse reaction, and related brain by t test and Pearson correlation analysis before and after treatment. RESULTS: Compared with pre-treatment, VAS score was significantly reduced (P<0.05), and no significant adverse reactions occurred after surgery. At the same time, the f-ALFF values of the left frontal gyrus, right frontal gyrus, left medial frontal cortex, right medial frontal cortex, and left inferior temporal gyrus were significantly enhanced (P<0.001). No significant correlation was found between f-ALFF changes in relevant brain areas and postoperative VAS changes and postoperative numbness. CONCLUSIONS: PRT treatment under CT-guidance can alleviate the pain of ITN patients, and it is safe and reliable. At the same time, the change of f-ALFF value in relevant brain regions provides a certain reference for the judgment of postoperative prognosis.

Key words: Resting state functional magnetic resonance, Primary trigeminal neuralgia, Percutaneous radiofrequency thermocoagulation, Brain function

CLC Number:

R745.1

WEN Ze-hui, WANG Yuan-yin, WANG Hai-bao, SONG Yang. Changes of cerebral frontal and temporal lobes after trigeminal ganglion radiofrequency thermocoagulation[J]. China Journal of Oral and Maxillofacial Surgery, 2020, 18(4): 319-322.

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