Expert consensus statement on diagnosis and clinical management of oral verrucous carcinoma

doi:10.19438/j.cjoms.2018.04.014

China Journal of Oral and Maxillofacial Surgery ›› 2018, Vol. 16 ›› Issue (4): 362-370.doi: 10.19438/j.cjoms.2018.04.014

• Expert Consensus • Previous Articles Next Articles

Expert consensus statement on diagnosis and clinical management of oral verrucous carcinoma

TANG Zhan-gui¹, BU Rong-fa², LIU Yan-pu³, GUO Wei⁴, SUN Mo-yi³, ZHENG Jia-wei⁴, HE Yue⁴, SHANG Zheng-jun⁵, WU Yu-nong⁶, LI Jin-song⁷, HAN Zheng-xue⁸, TIAN Zhen⁹, ZHANG Chen-ping⁴, LI Tie-jun¹⁰, ZHONG Ming¹¹, LIAO Gui-qing¹², SHEN Zi-hua¹, HUANG Jun-hui¹³, YU Jian-jun¹⁴, SU Tong¹⁵, YAO Zhi-gang¹³, HU Yan-jia¹

1.Department of Oral and Maxillofacial Surgery, Xiangya School of Stomatology, Central South University. Changsha 410013, Hunan Province;
2.Department of Oral and Maxillofacial Surgery, China PLA General Hospital. Beijing 100853;
3.Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University. Xi'an 710032, Shaanxi Province;
4. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
5.Department of Oral and Maxillofacial Surgery, School of Stomatology, Wuhan University. Wuhan 430072, Hubei Province;
6. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Nanjing Medical University. Nanjing 210029, Jiangsu Province;
7. Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Guangzhou 510120, Guangdong Province;
8. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Capital Medical University. Beijing 100050;
9.Department of Oral Pathology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
10. Department of Oral Pathology, School of Stomatology, Peking University. Beijing 100081;
11. Department of Oral Pathology, School of Stomatology, China Medical University. Shenyang 110122, Liaoning Province;
12. Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Sun Yat sen University. Guangzhou 510055, Guangdong Province;
13. Department of Oral Pathology, Xiangya School of Stomatology, Central South University. Changsha 410013, Hunan Province;
14. Department of Head and Neck Surgery, Hunan Provincial Tumor Hospital. Changsha 410006, Hunan Province;
15. Department of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University. Changsha 410008, Hunan Province, China

Received:2018-03-09 Revised:2018-03-28 Online:2018-07-20 Published:2018-08-09

Abstract

Abstract: Oral verrucous carcinoma (OVC) is a malignant tumor with independent histological changes and biological behaviors different from those of oral squamous cell carcinomas (OSCC). Its etiology is still unclear. It has the first clinical diagnosis coincidence rate of only 35% and is often misdiagnosed as other oral diseases such as verrucous hyperplasia, odontogenic keratocyst, aggressive periodontitis and chronic osteomyelitis. The treatment and prognosis of OVC are different from those of OSCC. Its misdiagnosis and mistreatment seriously affect patients' quality of life. In order to reduce misdiagnosis and mistreatment of OVC and to improve its early diagnostic rate, patients' survival rate and quality of life, it is necessary to establish an expert consensus on this tumor according to the national clinical conditions.

Key words: Oral verrucous carcinoma, OVC, Clinical diagnosis and management, Expert consensus

CLC Number:

R739.8

TANG Zhan-gui, BU Rong-fa, LIU Yan-pu, GUO Wei, SUN Mo-yi, ZHENG Jia-wei, HE Yue, SHANG Zheng-jun, WU Yu-nong, LI Jin-song, HAN Zheng-xue, TIAN Zhen, ZHANG Chen-ping, LI Tie-jun, ZHONG Ming, LIAO Gui-qing, SHEN Zi-hua, HUANG Jun-hui, YU Jian-jun, SU Tong, YAO Zhi-gang, HU Yan-jia. Expert consensus statement on diagnosis and clinical management of oral verrucous carcinoma[J]. China Journal of Oral and Maxillofacial Surgery, 2018, 16(4): 362-370.

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