Clinical analysis of 7 cases of 125I radioactive seed implant for recurrent palatal minor salivary gland malignancy

doi:10.19438/j.cjoms.2023.05.012

Abstract

Abstract: PURPOSE: To explore the effect of ¹²⁵I radioactive seed implant for recurrent palatal minor salivary gland malignancy. METHODS: Seven patients with palatal minor salivary gland malignancy who relapsed after surgery and radiotherapy and refused secondary surgery were treated with iodine 125 radioactive seed implant. According to the treatment planning system, iodine 125 radioactive seeds were implanted into the target area during surgery. Prosthesis-like applicators with radioactive seeds were wore according to the patients' conditions after surgery. The patients were followed up at regular intervals after operation and the treatment efficacy and side effects were evaluated. RESULTS: Tumor recurrence was not found in any patient treated after 17 to 62 months of follow-up. All patients did not show obvious radiation-related complications of grade 3 or more. During the follow-up, 1 elderly patient died of systemic disease and temporary mild adverse effects were noted in 3 patients. CONCLUSIONS: For patients with recurrent palatal minor salivary gland malignancy, iodine 125 radioactive seed implant has achieved good short-term efficacy and is a safe, minimally invasive, and effective treatment.

Key words: Palatal malignant tumor, Minor salivary gland tumor, Relapse, Iodine 125 radioactive seed, Brachytherapy

CLC Number:

R739.8

WANG Shou-peng, LI Sheng-nan, CHEN Lin, GE Liang-yu, LI Meng, MENG Jian. Clinical analysis of 7 cases of ¹²⁵I radioactive seed implant for recurrent palatal minor salivary gland malignancy[J]. China Journal of Oral and Maxillofacial Surgery, 2023, 21(5): 497-501.

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Clinical analysis of 7 cases of ¹²⁵I radioactive seed implant for recurrent palatal minor salivary gland malignancy

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