China Journal of Oral and Maxillofacial Surgery ›› 2023, Vol. 21 ›› Issue (3): 231-236.doi: 10.19438/j.cjoms.2023.03.004

• Original Articles • Previous Articles     Next Articles

Evaluation of the effect of coral hydroxyapatite bone block grafting in severe alveolar bone defects

ZHOU Chen1,2, WANG Wen-xue1,2, JIA Ren-jie3, LI Xin1, MEI Dong-mei1, LI Ya-nan1,2, ZHAO Bao-dong1,2   

  1. 1. Department of Oral Implantology, Affiliated Hospital of Qingdao University. Qingdao 266003;
    2. School of Stomatology, Qingdao University. Qingdao 266003;
    3. Department of Stomatology, Affiliated Qingdao Central Hospital of Qingdao University. Qingdao 266042, Shandong Province, China
  • Received:2022-11-23 Revised:2023-01-10 Online:2023-05-20 Published:2023-08-16

Abstract: PURPOSE: To evaluate the safety and efficacy of coral hydroxyapatite bone blocks in the treatment of severe alveolar bone defects. METHODS: Twenty-nine patients with severe alveolar bone defect were recruited from Jan 2019 to Jan 2021 in the Affiliated Hospital of Qingdao University. Thirteen patients underwent coral hydroxyapatite bone blocks grafting (CHA bone block group), 16 patients underwent autogenous bone blocks grafting (autogenous bone block group). To compare the bone augmentation and resorption between the two groups, CBCT was taken before (T0), immediately after (T1), 6 months after augmentation surgery(T2) and immediately after implant surgery(T3). The bone width of 0 mm (L1), 3 mm (L2), and 6 mm (L3) from the top of the alveolar ridge was measured. The pain intensity, complications (soft tissue dehiscence, infection or bone necrosis) after bone grafting were recorded. SPSS 26.0 software package was used for statistical analysis. RESULTS: All 29 patients were implanted successfully after bone grafting and finished restorations. The average follow-up was (13.28±4.34) months. There was no significant difference in bone augmentation and bone absorption 6 months after operation between the two groups(P>0.05). The pain response of CHA bone block group was significantly different from that of autologous bone block group(P<0.05). CONCLUSIONS: Coral hydroxyapatite bone block could be used for bone augmentation for severe horizontal bone defects, which could obtain bone mass required for implantation. There is no second operation area, less pain response, safe and effective. This technique might be accepted easily for patients, and is worthy of wide clinical application.

Key words: Coral hydroxyapatite, Autogenous bone, Bone regeneration, Bone defect

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