China Journal of Oral and Maxillofacial Surgery ›› 2021, Vol. 19 ›› Issue (1): 64-69.doi: 10.19438/j.cjoms.2021.01.013

• Evidence-Based Dentistry • Previous Articles     Next Articles

Effect of surgical therapy for patients with cranio-maxillo-facial fibrous dysplasia on visual acuity: a systematic review

LUO Dan1, LI Chen-xi2, GONG Zhong-cheng1   

  1. 1. Oncological Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Xinjiang Medical University, Stomatology School of Xinjiang Medical University, Stomatology Research Institute of Xinjiang Autonomous Region. Urumqi 830054, Xinjiang Autonomous Region, China;
    2. Department of Oral and Maxillofacial Surgery, Laboratory for Tumor Genetics and Regenerative Medicine, The Head and Neurocenter, University Medical Center Hamburg-Eppendorf UKE. Hamburg 20246, Germany
  • Received:2020-01-21 Revised:2020-06-04 Online:2021-01-20 Published:2021-02-19

Abstract: PURPOSE: To investigate the clinical effect and safety of surgical operation for patients who suffered from cranio-maxillo-facial fibrous dysplasia (CFD) on the aspect of visual acuity. METHODS: PubMed, Web of Science, Cochrane Library, Cochrane Clinical Trials Registration Center, CNKI, Wanfang database and VIP database were searched respectively and successively by computer up to now. All the patients who suffered from CFD were included, and the ones without visual impairment were defined as the experimental group, the other ones who got visual damage were defined as the control group. The total number of patients with visual impairment because of therapeutic surgery was extracted, and the data were processed in the way of meta-analysis. RESULTS: Fixed effect model was used for meta-analysis because there was good homogeneity between the studies (Chi2=8.63, df=9, P=0.47, I2=0%). Patients who had not visual impairment accepted surgery for their CFD as treatments and surgery did not increase the incidence of visual impairment[OR=0.39,95%CI(0.18-0.86),P=0.02]. There was no publication bias among the studies as well. CONCLUSIONS: Applying surgical operation for the treatment of CFD may not increase the possibility of visual impairment.

Key words: Cranio-maxillo-facial fibrous dysplasia, Surgical treatment, Optic nerve

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