Percutaneous radiofrequency ablation for children with Kasabach-Merritt phenomenon: a preliminary report

doi:10.19438/j.cjoms.2019.02.016

Abstract

Abstract: PURPOSE: To summarize the clinical experiences of percutaneous radiofrequency ablation for children with Kasabach-Merritt phenomenon(KMP), and to evaluate its clinical efficacy and safety. METHODS: From October 2014 to August 2015, three children with KMP in Linyi Tumor Hospital received percutaneous radiofrequency ablation. All patients received multiple treatments before admission without obvious curative effect, and the condition showed a trend of evolution. Percutaneous radiofrequency ablation (RFA) is based on "umbrella-like and dynamic" ablation techniques. The evaluation of primary lesions was based on the four scale grading system proposed by Achauer et al. The results of coagulation function evaluation were divided into ineffective, improved, significantly improved and cured. RESULTS: After follow-up for more than 3 years, one case achieved Achauer grade Ⅲ and 2 cases achieved Achauer grade Ⅳ of response for primary lesions of evaluation, and all 3 cases were evaluated as cured for coagulation function evaluation. Hyperpyrexia occurred in 3 patients,and one returned to normal 24 hours after ablation with intravenous dehydrocortisol, whereas the other 2 returned to normal 24 hours later without any medical intervention. CONCLUSIONS: Percutaneous radiofrequency ablation is an effective alternative therapy for KMP with definite efficacy, minimal injury and controllable complications, especially for deep and complex lesions.

Key words: Kaposiform hemangioendothelioma, Radiofrequency ablation, Kasabach-Merritt phenomenon

CLC Number:

R739.8

GE Chun-xiao, CHEN Tao, TAI Mao-zhong, LI Ke-lei, QIN Zhong-ping. Percutaneous radiofrequency ablation for children with Kasabach-Merritt phenomenon: a preliminary report[J]. China Journal of Oral and Maxillofacial Surgery, 2019, 17(2): 175-180.

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