Investigation of the treatment effect of pingyangmycin plus corticosteroids on cheilitis granulomatosa

doi:10.19438/j.cjoms.2018.02.012

Abstract

Abstract: PURPOSE: To explore the treatment effect of pingyangmycin plus corticosteroids on cheilitis granulomatosa. METHODS: A retrospective study on 78 patients with cheilitis granulomatosa treated by a new method at our hospital between March 2008 and March 2016 was performed. Pretherapeutic and post-therapeutic medical histories were obtained, and criteria for the success of treatment were evaluated. The outcomes and effects of therapy were analyzed. RESULTS: All patients received intralesional injection of pingyangmycin plus dexamethasone. The number of injections ranged from 1 to 5, with a median of 3 injections. The outcomes were encouraging. Seventy-three cases were cured, 5 cases were improved and none was found ineffective. Swelling of the lips subsided and the skin color returned to normal in all cases. In cases of orofacial involvement, facial asymmetry and orofacial swelling were removed to attain a good esthetic appearance. CONCLUSIONS: The results demonstrated positive responses to the treatment. It is a safe, effective and inexpensive treatment to correct persistent labial swelling and improve lip aesthetics.

Key words: Cheilitis granulomatosa, Melkersson-Rosenthal syndrome, Pingyangmycin, Corticosteroids, Dexamethasone

CLC Number:

R781.5.6

GU Ling, HUANG Di-yan, FU Chong-jian, WANG Zhao-ling, WANG Dong, YANG Lu, ZHU Guo-xiong. Investigation of the treatment effect of pingyangmycin plus corticosteroids on cheilitis granulomatosa[J]. China Journal of Oral and Maxillofacial Surgery, 2018, 16(2): 157-161.

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