中国口腔颌面外科杂志 ›› 2023, Vol. 21 ›› Issue (2): 206-208.doi: 10.19438/j.cjoms.2023.02.019

• 病例报告 • 上一篇    

下颌下腺腺样囊性癌高级别转化1例报告

胡永1, 王琼1, 赵大勇2, 叶金海3   

  1. 1.苏州科技城医院 口腔科,江苏 苏州 215153;
    2.上海交通大学医学院苏州九龙医院 口腔科,江苏 苏州 215028;
    3.南京医科大学附属口腔医院 口腔颌面外科,江苏 南京 210029
  • 收稿日期:2022-07-16 修回日期:2022-08-11 出版日期:2023-03-20 发布日期:2023-06-12
  • 通讯作者: 胡永,E-mail: hooyong@aliyun.com
  • 作者简介:胡永(1980-),男,博士,副主任医师
  • 基金资助:
    苏州市民生科技医疗卫生应用基础研究(SYSD2020082); 苏州高新区医疗卫生科技计划重点项目(2019Z013)

Adenoid cystic carcinoma with high grade transformation and sialolithiasis of the right submandibular gland: a rare case report

HU Yong1, WANG Qiong1, ZHAO Da-yong2, YE Jin-hai3   

  1. 1. Department of Stomatology, Suzhou Science & Technology Town Hospital. Suzhou 215153;
    2. Department of Stomatology, Suzhou Kowloon Hospital, School of Medicine, Shanghai Jiao Tong University. Suzhou 215028;
    3. Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University. Nanjing 210029, Jiangsu Province, China
  • Received:2022-07-16 Revised:2022-08-11 Online:2023-03-20 Published:2023-06-12

摘要: 下颌下腺腺样囊性癌高级别转化病例临床少见,同时伴发涎石者更为罕见。本文报告1例右侧下颌下腺腺样囊性癌伴高级别转化伴发涎石病例,在下颌下腺肿瘤扩大切除、选择性颈淋巴清扫和辅助放化疗后,肿瘤的低分化腺癌成分仍向肺、脊髓和脑转移。术后20个月,患者因转移瘤死亡。

关键词: 腺样囊性癌, 高级别转化, 下颌下腺, 涎石

Abstract: Adenoid cystic carcinoma(ACC) with high grade transformation(HGT) is rare, with the coexistence of a sialolith to be considered an extremely infrequent case. This article presented a case of ACC-HGT with sialolithiasis in the right submandibular gland, the poorly differentiated adenocarcinoma component of the tumor invaded the lung, spinal and brain after tumor resection, selective neck dissection and adjuvant radiotherapy and chemotherapy. The patient died twenty months after surgery due to metastases.

Key words: Adenoid cystic carcinoma, High grade transformation, Submandibular gland, Sialolithiasis

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