中国口腔颌面外科杂志 ›› 2015, Vol. 13 ›› Issue (3): 270-272.

• 综述 • 上一篇    下一篇

唾液腺淋巴上皮癌的研究进展

谈亦然, 钟来平   

  1. 上海交通大学医学院附属第九人民医院·口腔医学院 口腔颌面-头颈肿瘤科,上海市口腔医学重点实验室,上海 200011
  • 收稿日期:2014-01-08 修回日期:2014-11-24 出版日期:2015-05-20 发布日期:2015-06-18
  • 通讯作者: 钟来平,E-mail: zhonglaiping@163.com
  • 作者简介:谈亦然(1988- ),男,口腔医学7年制学生,E-mail: gordon-tan@hotmail.com

Research progress on lymphoepithelial carcinoma of salivary gland

TAN Yi-ran, ZHONG Lai-ping   

  1. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China
  • Received:2014-01-08 Revised:2014-11-24 Online:2015-05-20 Published:2015-06-18

摘要: 唾液腺淋巴上皮癌是原发于唾液腺的一种较为罕见的恶性肿瘤,最早于1962年由Hilderman首次报道并提出,曾有多个别名,如淋巴上皮瘤样癌、恶性淋巴上皮病变、伴淋巴样间质的未分化癌以及癌在淋巴上皮病变中。WHO头颈肿瘤分类第3版(2005年)正式将其更名为淋巴上皮癌。唾液腺淋巴上皮癌的临床诊治尚未规范。本文旨在针对唾液腺淋巴上皮癌的发病机制、临床病理特点、诊断、治疗和预后进行综述。

关键词: 唾液腺, 淋巴上皮癌, EB病毒

Abstract: Lymphoepithelial carcinoma of salivary gland is a rare primary carcinoma in salivary gland. It was first described by Hilderman in 1962. It had different designation in the literatures as lymphoepithelioma-like carcinoma, malignant lymphoepithelial lesion, undifferentiated carcinoma with lymphoid stroma, carcinoma in lymphoepithelial lesion. It was finally defined as lymphoepithelial carcinoma in histological classification of salivary gland tumors (version 3 of pathology and genetics of head and neck tumors in World Health Organization classification of tumors in 2005). There is still no standard treatment guideline for lymphoepithelial carcinoma of salivary gland, the paper briefly reviewed current progress on lymphoepithelial carcinoma of salivary gland on the aspects of carcinogenesis, clinical and pathological features, diagnosis, treatment and prognosis to improve the comprehensive understanding of this disease.

Key words: Salivary gland, Lymphoepithelial carcinoma, Epstein-Barr virus

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