新疆地区133例口腔颌面部间隙感染临床分析

中国口腔颌面外科杂志 ›› 2016, Vol. 14 ›› Issue (1): 28-32.

新疆地区133例口腔颌面部间隙感染临床分析

郭治辰，龚忠诚^*，林兆全^*，凌彬，刘慧， KarmeshBajracharya

新疆医科大学第一附属医院口腔颌面肿瘤外科,新疆乌鲁木齐 830054

收稿日期:2015-06-09 出版日期:2016-01-20 发布日期:2016-02-01
通讯作者: 龚忠诚,Tel:0991-4366079, E-mail：gump0904@aliyun.com;林兆全,Tel:0991-4366081 , E-mail:lzqxhj@163.com。*共同通信作者
作者简介:郭治辰（1988-）,男,在读硕士研究生,E-mail:309091585@qq.com
基金资助:
国家自然科学基金（31260229）; 新疆维吾尔自治区青年科技创新人才培养工程项目（2014721046）

Retrospective analysis of 133 patients with oral and maxillofacial space infection in Xinjiang region

GUO Zhi-chen, GONG Zhong-cheng, LIN Zhao-quan, LING Bin, LIU Hui, KARMESH Bajracharya

Department of Oral and Maxillofacial Oncology, The First Affiliated Hospital of Xinjiang Medical University. Urumqi 830054, Xinjiang Uygur Autonomous Region, China

Received:2015-06-09 Online:2016-01-20 Published:2016-02-01

摘要/Abstract

摘要： 目的通过分析新疆地区口腔颌面部间隙感染（oral and maxillofacial space infection,OMSI）患者的一般情况、临床症状、感染来源及分布、治疗和并发症,探讨引起致命并发症的危险因素,为其防治提供依据。方法收集2013年5月—2015年5月期间新疆医科大学第一附属医院口腔颌面外科收治的133例OMSI患者的病例资料,采用SPSS16.0软件包对患者的一般情况与并发症的关系进行单因素和多因素分析。结果 133例患者中,男性占52.6%,女性占47.4%;平均年龄45.9岁,症状出现到入院平均间隔时间为23.8 d,平均住院10.3 d。糖尿病患者47例（35.3%）。最常见的感染途径为牙源性感染（35例,26.3%）,常累及咬肌间隙;最常见的非牙源性感染为腺源性感染（15例,11.2%）,颏下间隙常受累。22例患者（16.5%）出现并发症,多间隙受累和白细胞计数≥15×10⁹/L是并发症发生的独立危险因素。结论多间隙感染和白细胞计数≥15×10⁹/L的OMSI患者、合并糖尿病的患者很容易出现严重并发症,危及生命,临床上需给予密切关注与重视。

关键词: 口腔颌面部间隙感染, 非牙源性感染, 牙源性感染, 并发症

Abstract: PURPOSE : A retrospective study on the characteristics of patient, clinical symptoms, etiology of oral and maxillofacial space infection and involved spaces, treatment and complications in Xinjiang Uygur Autonomous Region was carried out, in order to identify factors predisposing to life-threatening complications and provide references for prevention of complications. METHODS : The clinical data of 133 patients with oral and maxillofacial infection treated in the Department of Oral and Maxillofacial Surgery of the First Affiliated Hospital of Xinjiang Medical University were retrospectively analyzed from May 2013 to May 2015.Univariate analysis and multivariate analysis were done for identifying associations of patient characteristics with complications by SPSS 16.0 software package. RESULTS : Out of 133 patients identified, 52.6% were male, 47.4% were female. The average interval time from presence of symptoms to hospitalization was 23.8 days. The mean age of patients was 45.9 years and 35.3% of the patients had diabetes. The most common odontogenic infection was periapical periodontitis. Thirty-five (26.3%) patients had pupal infection. The most commonly involved space was massteric space. In non-odontogenic infection, the most common origin was glandular infection with 15 cases(11.2%). The most commonly involved space was submental space. Twenty two patients (16.5%) developed complications. Multiple space involvement and leukocyte count≥15×10⁹/L were independent predictors of complications. CONCLUSIONS : Patients with oral and maxillofacial space infection who present multiple space involvement, a high leukocyte count, and those with diabetes are the higher risk factors of developing life-threatening complications and need to be closely monitored.

Key words: Oral and maxillofacial space infection, Odontogenic infection, Non-odontogenic infection, Complications

中图分类号:

R782.3

郭治辰，龚忠诚，林兆全，凌彬，刘慧， KarmeshBajracharya. 新疆地区133例口腔颌面部间隙感染临床分析[J]. 中国口腔颌面外科杂志, 2016, 14(1): 28-32.

GUO Zhi-chen, GONG Zhong-cheng, LIN Zhao-quan, LING Bin, LIU Hui, KARMESH Bajracharya. Retrospective analysis of 133 patients with oral and maxillofacial space infection in Xinjiang region[J]. China J Oral Maxillofac Surg, 2016, 14(1): 28-32.

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