成年打鼾人群患阻塞性睡眠呼吸暂停的危险因素分析

doi:10.19438/j.cjoms.2024.02.004

中国口腔颌面外科杂志 ›› 2024, Vol. 22 ›› Issue (2): 137-142.doi: 10.19438/j.cjoms.2024.02.004

成年打鼾人群患阻塞性睡眠呼吸暂停的危险因素分析

郑彤^*, 姚侃^*, 钱轶峰, 孙红霞, 卢晓峰^#, 于雯雯^#

上海交通大学医学院附属第九人民医院口腔颅颌面科,上海交通大学口腔医学院,国家口腔医学中心, 国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海 200011

收稿日期:2023-06-26 修回日期:2023-08-07 发布日期:2024-03-27
通讯作者: 卢晓峰,E-mail: lukeluxf@163.com;于雯雯,E-mail: ywwyww2015@126.com。^#共同通信作者
作者简介:郑彤（1995-）,女,硕士,E-mail: yoyo51228@sina.com;姚侃（1990-）,男,硕士,E-mail: discant@163.com。^*并列第一作者
基金资助:
国家自然科学基金青年项目（81800992）

Risk factors for obstructive sleep apnea in snoring adults

ZHENG Tong^*, YAO Kan^*, QIAN Yi-feng, SUN Hong-xia, LU Xiao-feng^#, YU Wen-wen^#

Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Received:2023-06-26 Revised:2023-08-07 Published:2024-03-27

摘要/Abstract

摘要： 目的: 探索成年打鼾人群罹患阻塞性睡眠呼吸暂停的相关危险因素,尝试性提出新型预测工具。方法: 采用横断面研究,对2012年1月—2021年10月于上海交通大学医学院附属第九人民医院睡眠医学中心进行整夜多导睡眠监测(polysomnography, PSG)的成年打鼾人群进行数据收集,依据睡眠呼吸暂停低通气指数(apnea hyponea index, AHI)进行阻塞性睡眠呼吸暂停(obstructive sleep apnea, OSA)患病与否分组,分为非OSA组与OSA组,对成年打鼾人群OSA患病危险因素进行分析。结果: 纳入研究对象1 155例,整体OSA患病率为88.23%,患者男女比例为4.12∶1。成年打鼾人群罹患OSA的危险因素是年龄、颈围/身高比、性别、腰围,相应预警值为30.5岁、22.93、男性、86.25 cm。对于成年打鼾人群,提出OSA预测工具WRAG-N,预测OSA的AUC为0.789,灵敏度为87.2%,特异度为29.4%。结论对于成年打鼾人群,30岁以上、男性、腰围大于86.25cm是OSA患病的危险因素,颈围/身高比是OSA患病与否的关键危险因素之一。作为罹患OSA的新型预测工具,WRAG-N有助于基层社区筛查成年打鼾高危人群,及时进行预防及诊治。

关键词: 成人, 打鼾, 阻塞性睡眠呼吸暂停, 危险因素

Abstract: PURPOSE: To explore the risk factors for obstructive sleep apnea in snoring adults. METHODS: A cross-sectional study was conducted in 1 155 adult snoring patients who were overnight polysomnography(PSG) monitored for obstructive sleep apnea(OSA) from January 2012 to October 2021 in Sleep Medicine Center of Shanghai Ninth People's Hospital. The patients were divided into two groups based on apnea hypopnea index (AHI): non-OSA and OSA groups. The prevalence and risk factors of OSA were analyzed. RESULTS: The prevalence of OSA was 88.23%, and the male to female ratio was 4.12∶1. The risk factors for OSA in snoring adults were age, neck circumference/height ratio, gender and waist circumference, of which the thresholds were 30.5 years old, 22.93, male, 86.25 cm. WRAG-N was proposed to predict OSA, with an AUC of 0.789, a sensitivity of 87.2%, and a specificity of 29.4%. CONCLUSIONS: For adult snoring population, the risk factors for OSA were over 30 years old, male and waist circumference greater than 86.25 cm. Meanwhile, neck circumference/height ratio is one of the key risk factors for OSA. WRAG-N, innovatively proposed as the predictive tool for OSA, may help communities screen OSA in high-risk snoring adults to provide efficient and high-quality diagnosis and treatment.

Key words: Adult, Snoring, Obstructive sleep apnea, Risk factors

中图分类号:

R782.2

郑彤, 姚侃, 钱轶峰, 孙红霞, 卢晓峰, 于雯雯. 成年打鼾人群患阻塞性睡眠呼吸暂停的危险因素分析[J]. 中国口腔颌面外科杂志, 2024, 22(2): 137-142.

ZHENG Tong, YAO Kan, QIAN Yi-feng, SUN Hong-xia, LU Xiao-feng, YU Wen-wen. Risk factors for obstructive sleep apnea in snoring adults[J]. China J Oral Maxillofac Surg, 2024, 22(2): 137-142.

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成年打鼾人群患阻塞性睡眠呼吸暂停的危险因素分析

Risk factors for obstructive sleep apnea in snoring adults

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