腮腺区复发性多形性腺瘤恶变侵犯颧骨1例报告

doi:10.19438/j.cjoms.2021.06.017

中国口腔颌面外科杂志 ›› 2021, Vol. 19 ›› Issue (6): 573-576.doi: 10.19438/j.cjoms.2021.06.017

• 病例报告 • 上一篇

腮腺区复发性多形性腺瘤恶变侵犯颧骨1例报告

许飞虎¹, 徐万林^2,*, 刘胜文², 丁修明¹, 张祥¹, 杨雯君^2,*

1. 南通大学附属海安医院口腔科,江苏南通 226600;
2. 上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海 200011

出版日期:2021-12-25 发布日期:2022-03-02
通讯作者: 徐万林,E-mail：xwlcontribution@163.com;杨雯君,E-mail：ywjdoctor@163.com。*共同通信作者
作者简介:许飞虎（1986-），男，本科，E-mail: 1072677680@qq.com
基金资助:
上海市科委青年科技扬帆计划（21YF1423500）；上海交通大学医学院附属第九人民医院生物样本库项目（YBKB201920）

A case report of malignant transformation of parotid recurrent pleomorphic adenoma invading the zygoma

XU Fei-hu¹, XU Wan-lin², LIU Sheng-wen², DING Xiu-ming¹, ZHANG Xiang¹, YANG Wen-jun²

1. Department of Stomatology, Affiliated Haian Hospital of Nantong University. Nantong 226600, Jiangsu Province;
2. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China

Online:2021-12-25 Published:2022-03-02

摘要/Abstract

摘要： 腮腺区复发性多形性腺瘤（recurrent pleomorphic adenoma，RPA）存在一定的恶变几率，但检索国内外文献未见侵犯颧骨的报道。本文报告1例腮腺区复发性多形性腺瘤恶变侵犯颧骨病例，并结合相关文献分析其临床、影像及病理特点，以进一步提高对该病的认识，减少误诊误治。

关键词: 腮腺肿瘤, 多形性腺瘤, 复发性多形性腺瘤, 癌在多形性腺瘤中

Abstract: [Summary] Recurrent pleomorphic adenoma in the parotid region has certain probability of malignant transformation, but until now there is no report of zygomatic invasion in the literatures. This article reported a case of recurrent pleomorphic adenoma in parotid region with malignant transformation and invasion of the zygoma, and analyzed its clinical, imaging and pathological characteristics based on literature review, so as to improve our understanding of this disease and avoid misdiagnosis and mistreatment.

Key words: Parotid tumor, Pleomorphic adenoma, Recurrent pleomorphic adenoma, Carcinoma ex pleomorphic adenoma

中图分类号:

R739.8

许飞虎, 徐万林, 刘胜文, 丁修明, 张祥, 杨雯君. 腮腺区复发性多形性腺瘤恶变侵犯颧骨1例报告[J]. 中国口腔颌面外科杂志, 2021, 19(6): 573-576.

XU Fei-hu, XU Wan-lin, LIU Sheng-wen, DING Xiu-ming, ZHANG Xiang, YANG Wen-jun. A case report of malignant transformation of parotid recurrent pleomorphic adenoma invading the zygoma[J]. China J Oral Maxillofac Surg, 2021, 19(6): 573-576.

参考文献

[1] Tian Z, Li L, Wang L, et al.Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6 982 cases in an eastern Chinese population[J]. Int J Oral Maxillofac Surg, 2010, 39(3): 235-242.
[2] Valstar MH, de Ridder M, van den Broek EC, et al. Salivary gland pleomorphic adenoma in the Netherlands: a nationwide observational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence[J]. Oral Oncol, 2017, 66(1): 93-99.
[3] Witt RL, Eisele DW, Morton RP, et al.Etiology and management of recurrent parotid pleomorphic adenoma[J]. Laryngoscope, 2015, 125(4): 888-893.
[4] Mantsopoulos K, Iro H.Tumour spillage of the pleomorphic adenoma of the parotid gland: a proposal for intraoperative measures[J]. Oral Oncol, 2021, 112: 104986.
[5] 徐万林, 朱云, 卢浩, 等. 15例下颌下腺复发性多形性腺瘤临床病理分析[J]. 中国口腔颌面外科杂志, 2019, 17(5): 465-468.
[6] Andreasen S, Therkildsen MH, Bjφrndal K, et al.Pleomorphic adenoma of the parotid gland 1985-2010: a Danish nationwide study of incidence, recurrence rate, and malignant transformation[J]. Head neck, 2016, 38(Suppl 1): E1364-E1369.
[7] Makeieff M, Pelliccia P, Letois F, et al.Recurrent pleomorphic adenoma: results of surgical treatment[J]. Ann Surg Oncol, 2010, 17(12): 3308-3313.
[8] Seethala RR, Stenman G.Update from the 4th edition of the World Health Organization classification of head and neck tumours: tumors of the salivary gland[J]. Head Neck Pathol, 2017, 11(1): 55-67.
[9] Alshagroud R, Kamoh A, Popat SR, et al.Metastasizing pleomorphic adenoma case report and review of the literature[J]. Head Neck Pathol, 2017, 11(4): 487-493.
[10] Ojha J, Bhattacharyya I, Islam MN, et al.Intraosseous pleomorphic adenoma of the mandible: report of a case and review of the literature[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2007, 104(2): e21-e26.
[11] Ferretti C, Coleman H, Altini M, et al.Intraosseous myoepithelial neoplasms of the maxilla: diagnostic and therapeutic considerations in 5 South African patients[J]. J Oral Maxillofac Surg, 2003, 61(3): 379-386.
[12] Aver-De-Araujo LM, Chaves-Tarquinio SB, Neuzling-Gomes AP, et al. Intraosseous pleomorphic adenoma: case report and review of the literature[J]. Med Oral, 2002, 7(3): 164-170.
[13] Koyama M, Terauchi T, Koizumi M, et al.Metastasizing pleomorphic adenoma in the multiple organs: a case report on FDG-PET/CT imaging[J]. Medicine (Baltimore), 2018, 97(23): e11077.
[14] Kanatas A, Ho MWS, Mucke T.Current thinking about the management of recurrent pleomorphic adenoma of the parotid: a structured review[J]. Br J Oral Maxillofac Surg, 2018, 56(4): 243-248.
[15] Thielker J, Grosheva M, Ihrler S, et al.Contemporary management of benign and malignant parotid tumors[J]. Front Surg, 2018, 5: 39-56.
[16] Nicholas SE, Vujaskovic L, DeLuna R, et al. Complete resection and adjuvant radiation yield improved local control in patients with recurrent pleomorphic adenoma[J]. Int J Radiat Oncol Biol Phys, 2017, 99(2): E362-E362.
[17] Wittekindt C, Streubel K, Arnold G, et al.Recurrent pleomorphic adenoma of the parotid gland: analysis of 108 consecutive patients[J]. Head neck, 2007, 29(9): 822-828.

腮腺区复发性多形性腺瘤恶变侵犯颧骨1例报告

A case report of malignant transformation of parotid recurrent pleomorphic adenoma invading the zygoma

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 14

编辑推荐

Metrics

本文评价

[1]	瞿俊晨, 贾传海, 丁庆国, 曹锐, 丘佳明. MRI图像纹理分析在腮腺良、恶性肿瘤鉴别诊断中的价值[J]. 中国口腔颌面外科杂志, 2022, 20(2): 173-176.
[2]	陈泽源, 刘怡彬, 再米热·依布拉音, 张思敏, 买买提吐逊·吐尔地. 腮腺超声造影对43例腮腺肿瘤的诊断价值评价[J]. 中国口腔颌面外科杂志, 2022, 20(2): 177-183.
[3]	孙琦, 马超, 董敏俊, 陶晓峰. 感兴趣区大小选择对多形性腺瘤和腺淋巴瘤ADC测量的影响[J]. 中国口腔颌面外科杂志, 2021, 19(1): 29-35.
[4]	苑绪光, 朱骏飞, 李天竹, 光梦凯, 张晔. 同侧腮腺同时存在2种不同肿瘤1例报告[J]. 中国口腔颌面外科杂志, 2021, 19(1): 94-96.
[5]	汪洋, 夏亮, 胡宇华, 张春叶, 王丽珍, 李江, 田臻. 基于RNA-Seq分析挖掘唾液腺多形性腺瘤核心基因及通路[J]. 中国口腔颌面外科杂志, 2019, 17(5): 397-402.
[6]	徐万林, 朱云, 卢浩, 刘丽敏, 沈淑坤, 刘胜文, 杨雯君. 15例下颌下腺复发性多形性腺瘤临床病理分析[J]. 中国口腔颌面外科杂志, 2019, 17(5): 465-468.
[7]	魏军水, 卢浩, 杨雯君, 沈淑坤, 徐万林. 人多形性腺瘤中与cyclin D1共表达LncRNA的初步筛选及鉴定[J]. 中国口腔颌面外科杂志, 2019, 17(3): 198-203.
[8]	徐万林, 刘丽敏, 卢浩, 杨雯君, 沈淑坤. PLAG1转基因小鼠中差异表达长链非编码RNA的筛选分析[J]. 中国口腔颌面外科杂志, 2019, 17(1): 20-25.
[9]	夏亮, 汪洋, 胡宇华, 王丽珍, 顾挺, 李江, 田臻. HER2基因在唾液腺恶性多形性腺瘤细胞增殖、周期、凋亡中的作用[J]. 中国口腔颌面外科杂志, 2018, 16(4): 310-316.
[10]	夏亮, 胡宇华, 王丽珍, 顾挺, 李江, 田臻. 唾液腺恶性多形性腺瘤中CDH1基因启动子甲基化与E-cadherin表达的相关性分析[J]. 中国口腔颌面外科杂志, 2018, 16(2): 120-125.
[11]	夏亮, 汪洋, 胡宇华, 顾挺, 李江, 石慧敏, 田臻. 唾液腺恶性多形性腺瘤HER2基因扩增与临床病理特征及预后的关系[J]. 中国口腔颌面外科杂志, 2018, 16(1): 12-19.
[12]	邓刚，李晓光，何悦，于德栋. 复发性腮腺多形性腺瘤的手术治疗及并发症预防[J]. 中国口腔颌面外科杂志, 2017, 15(3): 227-229.
[13]	夏亮, 张春叶, 胡宇华, 钱佳骏, 李江, 田臻. 启动子甲基化状况对唾液腺恶性多形性腺瘤体外细胞系细胞E-cadherin表达的影响[J]. 中国口腔颌面外科杂志, 2016, 14(4): 308-314.
[14]	王友元, 张大明, 范松, 王磊, 黄志权, 杨朝晖, 李劲松, 陈伟良. 婴儿腮腺成涎细胞瘤手术治疗的初步探讨[J]. 中国口腔颌面外科杂志, 2015, 13(2): 167-170.