中国口腔颌面外科杂志 ›› 2017, Vol. 15 ›› Issue (6): 488-492.doi: 10.19438/j.cjoms.2017.06.011

• 论著 • 上一篇    下一篇

2型糖尿病血糖控制水平对种植体稳定性和血液炎症指标的影响

张晓东, 刘茜, 张民主, 王敏, 朱坤   

  1. 蚌埠医学院第二附属医院 口腔科,安徽 蚌埠 233000
  • 收稿日期:2017-01-20 修回日期:2017-05-25 出版日期:2017-11-20 发布日期:2017-12-21
  • 通讯作者: 张晓东,E-mail: 1573702676@qq.com
  • 作者简介:张晓东(1966-),男,学士,主任医师

Effect of blood glucose control on the stability of implant and the indexes of blood inflammation in patients with type 2 diabetes mellitus

ZHANG Xiao-dong, LIU Xi, ZHANG Min-zhu, WANG Min, ZHU Kun   

  1. Department of Dentistry, The Second Affiliated Hospital of Bengbu Medical College. Bengbu 233000, Anhui Province, China
  • Received:2017-01-20 Revised:2017-05-25 Online:2017-11-20 Published:2017-12-21

摘要: 目的 探究2型糖尿病血糖控制水平对种植体稳定性和血液炎症指标的影响。方法 选取2014年7月—2015年7月于我院接受种植牙手术的30例2型糖尿病患者作为实验组,另选取30例同期血糖正常的种植牙患者作为对照组,比较并分析两组的血糖控制水平、种植体稳定性以及血液炎症指标。采用SPSS 18.0软件包对数据进行统计学分析。结果 术前2组各炎症指标差异均不显著(P>0.05),术后24 h实验组各炎症指标水平均显著高于对照组(P<0.05);术后ISQ呈下降后迅速回升并增强的趋势,各组各时间点的ISQ差异均无统计学意义(P>0.05);>7.5%组的ISQ最大下降值低于≤7.5%组,且ISQ恢复时间显著长于≤7.5%组。结论 2型糖尿病血糖控制水平与种植体稳定性、血液炎症指标均存在密切关系,良好的血糖控制对患者的创伤愈合和种植体的稳定性具有积极意义。

关键词: 2型糖尿病, 血糖控制, 牙种植体, 稳定性, 炎症

Abstract: PURPOSE: To investigate the effect of blood glucose control on the stability of the implant and the indexes of blood inflammation in type 2 diabetes mellitus. METHODS: From July 2014 to July 2015, 30 patients with type 2 diabetes undergoing dental implantation were chosen as the experimental group, while 30 patients with normal blood glucose who underwent dental implantation were chosen as control group. Blood glucose control level, implant stability and blood inflammatory markers were compared between the two groups using SPSS 18.0 software package. RESULTS: Preoperatively inflammatory markers were not significantly different (P>0.05) between the two groups; 24 h postoperatively, inflammatory indexes in the experimental group were significantly higher than those in the control group (P<0.05); postoperative ISQ decreased rapidly and then raised, but no difference was found at each time point in 2 groups (P>0.05); maximum decrease of ISQ in patients with blood glucose >7.5% was lower than in patients with blood glucose less than or equal to 7.5%, and the recovery time of ISQ was significantly longer. CONCLUSIONS: The level of blood glucose control in type 2 diabetes mellitus is closely related to the stability of dental implant and the indexes of blood inflammation.

Key words: TMJ anchorage surgery, Condyle of mandible, Anchoring nail, Anchoring line, Analysis of pullout force

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