中国口腔颌面外科杂志 ›› 2017, Vol. 15 ›› Issue (1): 63-68.doi: 10.19438/j.cjoms.2017.01.014

• 论著 • 上一篇    下一篇

UPPP术后短期上气道重塑现象的初步探讨

姚侃, 王猛, 于雯雯, 胥雷, 魏思龙, 孙红霞, 卢晓峰   

  1. 上海交通大学医学院附属第九人民医院·口腔医学院 口腔颅颌面科, 上海市口腔医学重点实验室,上海 200011
  • 出版日期:2017-01-20 发布日期:2017-02-27
  • 通讯作者: 卢晓峰,E-mail:lukeluxf@yahoo.com
  • 作者简介:姚侃(1990-),男,硕士,E-mail:discant@163.com

Preliminary study of the short-time remolding of upper airway after uvulopalatopharyngoplasty

YAO Kan, WANG Meng, YU Wen-wen, XU Lei, WEI Si-long, SUN Hong-xia, LU Xiao-feng   

  1. (Department of Oral and Craniomaxillofacial Science, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China)
  • Online:2017-01-20 Published:2017-02-27

摘要: 目的 评估腭垂腭咽成形术(uvulopalatopharyngoplasty, UPPP)术前、术后第3天及1、2、3、6个月时上气道及舌骨位置的变化速率,验证UPPP术后短期上气道重塑的现象。方法 选择2013年11月—2014年9月期间于上海交通大学医学院附属第九人民医院就诊并接受UPPP术的21例成年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者(平均年龄36.58±3.47岁),术前、术后第3天及1、2、3、6个月时拍摄头颅定位侧位片及"i"音位片。通过AUTOCAD 2015测量,得到各时间点的上气道不同区域(鼻咽、腭咽、舌咽及喉咽气道)前后径及舌骨位置参数(垂直向与水平向),利用SAS 8.02软件包比较各参数之间的差异,分析评估UPPP术后短期上气道的重塑现象。结果 UPPP术的创伤主要影响腭咽及舌咽气道,腭咽及舌咽参数缩小(P<0.05),同时UPPP可导致舌骨位置向后下移位(P<0.05)。UPPP术后上气道及舌骨位置参数持续改变,鼻咽气道在术后1~6个月无显著变化(P>0.05),腭咽气道前后径在术后持续增加(P<0.05),舌咽气道前后径在术后1月显著增加(P<0.05)。喉咽气道前后径在术后2~6个月逐步减小(P<0.05),舌骨位置总体向后下下降(P<0.05),但在术后1个月内舌骨位置处于上升状态(P<0.05)。结论 UPPP术后6个月内上气道存在重塑现象。

关键词: 睡眠呼吸障碍, 腭垂腭咽成形术, 气道重塑

Abstract: PURPOSE: To explore the remolding of upper airway in patients with obstructive sleep apnea-hyponea syndrome (OSAHS) after uvulopalatopharyngoplasty (UPPP). METHODS: Twenty-one male adult patients aged 27 to 52 years were included and followed up from pre-operation to 6 months after operation. Lateral cephalometric radiographs (conventional and when pronouncing "i" ) were taken before operation and 3 days, 1, 2, 3, 6 months after operation. The anterolateral diameters of different level of upper airway and parameters of hyoid position at each time point were measured by AUTOCAD 2015. SAS 8.02 software package was used to analyze the difference. RESULTS: UPPP mainly affected the velopharyngeal and glossopharyngeal areas: parameters wane (P<0.05). On the other hand, UPPP led to the decline and retrusion of hyoid. The nasopharynx kept statical (P>0.05) while the velopharyngeal parameters were increased (P<0.05) with reducing velocities (P<0.05). The glossopharyngeal parameters increased in the first month after UPPP (P<0.05), while hypopharyngeal parameters underwent decline since 2 months after UPPP (P<0.05). The hyoid underwent decline and retrusion (P<0.05) , while endured a short-time increase in the first month after UPPP (P<0.05). CONCLUSIONS: Short-time upper airway remolding after UPPP does exist.

Key words: OSAHS, UPPP, Airway remolding

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