口腔癌患者术后舌神经功能障碍与生活质量的关系评价

doi:10.19438/j.cjoms.2022.05.006

中国口腔颌面外科杂志 ›› 2022, Vol. 20 ›› Issue (5): 449-454.doi: 10.19438/j.cjoms.2022.05.006

口腔癌患者术后舌神经功能障碍与生活质量的关系评价

吴梓谦^1#, 殷玉兰^2#, 杨文玉¹, 张贞¹, 侯黎莉^3,*, 王磊^1,*

1.上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海 200011;
2.上海市奉贤区奉城医院口腔科,上海 201411;
3.上海交通大学医学院附属第九人民医院护理部,上海 200011

收稿日期:2022-05-17 修回日期:2022-08-12 出版日期:2022-09-20 发布日期:2022-09-20
通讯作者: 王磊,E-mail: wangleizyh@aliyun.com;侯黎莉, E-mail: pisces_liz@163.com。^*共同通信作者
作者简介:吴梓谦（1997-）,男,在读硕士研究生,E-mail: wuziqian64@163.com;殷玉兰（1971-）,女,E-mail: 975897621@qq.com。^#并列第一作者
基金资助:
国家自然科学基金(81970907,81771046); 上海交通大学医学院附属第九人民医院临床助推项目(JYLJ201817)

Relationship between postoperative lingual nerve dysfunction and quality of life in oral cancer patients

WU Zi-qian¹, YIN Yu-lan², YANG Wen-yu¹, ZHANG Zhen¹, HOU Li-li³, WANG Lei¹

1. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology. Shanghai 200011;
2. Department of Stomatology, Fengcheng Hospital. Shanghai 201411;
3. Nursing Department, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China

Received:2022-05-17 Revised:2022-08-12 Online:2022-09-20 Published:2022-09-20

摘要/Abstract

摘要： 目的: 通过自制问卷,调查口腔癌根治术后出现舌神经损伤患者的口腔功能及生活质量情况,为临床上管理舌神经损伤患者提供依据。方法: 通过对350例患者进行定性感觉分析,筛选出其中存在舌感觉麻木症状的40例患者,采用自制《舌感觉功能障碍康复问卷》进行问卷调查。结果: 调查结果显示,舌感觉功能障碍5种最常见表现依次为①对于感觉的改变无法恢复的恐惧感;②难以做出需要舌参与的表情;③讲话时遇到困难;④无法意识到口底或舌头上的食物残留以维持口腔卫生;⑤因舌感觉的改变而难以入眠。结论: 舌感觉功能障碍从多方面导致生活质量下降,口腔颌面外科医护人员应加强对舌神经损伤的围术期评估和管理。

关键词: 口腔癌, 问卷调查, 舌神经, 生活质量

Abstract: PURPOSE: To investigate the oral function and quality of life of patients presenting with lingual nerve injury after radical surgery for oral cancer by means of a self-administered questionnaire, to provide a basis for the clinical management of patients with lingual nerve injury. METHODS: Through qualitative sensory analysis of 350 patients, forty patients with tongue sensory numbness were screened out, and the questionnaire was conducted by self-made Rehabilitation Questionnaire of Tongue Sensory Dysfunction. RESULTS: According to the results, the 5 most common manifestations of tongue sensory dysfunction were ①fear of not recovering from altered sensation; ② difficulty in making expressions that require tongue involvement; ③difficulty in speaking; ④inability to be aware of food residue on the floor of the mouth or tongue to maintain oral hygiene; ⑤difficulty in sleeping due to altered tongue sensation. CONCLUSIONS: The decline in quality of life due to tongue sensory dysfunction is multifaceted and oral and maxillofacial surgery providers should enhance the perioperative assessment and management of lingual nerve injury.

Key words: Oral cancer, Questionnaire survey, Lingual nerve, Quality of life

中图分类号:

R739.8

吴梓谦, 殷玉兰, 杨文玉, 张贞, 侯黎莉, 王磊. 口腔癌患者术后舌神经功能障碍与生活质量的关系评价[J]. 中国口腔颌面外科杂志, 2022, 20(5): 449-454.

WU Zi-qian, YIN Yu-lan, YANG Wen-yu, ZHANG Zhen, HOU Li-li, WANG Lei. Relationship between postoperative lingual nerve dysfunction and quality of life in oral cancer patients[J]. China J Oral Maxillofac Surg, 2022, 20(5): 449-454.

参考文献

[1] Miloro M, Zuniga JR, Meyer RA.How many oral surgeons does it take to classify a nerve injury?[J]. J Oral Maxillofac Surg, 2021, 79(7): 1550-1556.
[2] Rogers SN, Lowe D, Yueh B, et al.The physical function and social-emotional function subscales of the University of Washington Quality of Life Questionnaire[J]. Arch Otolaryngol Head Neck Surg, 2010, 136(4): 352-357.
[3] 袁灏, 沈国芳, 王旭东. 下颌支矢状劈开截骨术后下唇感觉功能障碍对生活质量的影响[J]. 中国修复重建外科杂志, 2007, 21(9): 957-960.
Yuan H, Shen GF,Wang XD.Effect of sensory disturbance on living quality after a sagittal split ramus osteotomy[J]. Chinese Journal of Reparative and Reconstructive Surgery, 2007, 21(9): 957-960.
[4] Namin AW, Varvares MA.Functional outcomes of sensate versus insensate free flap reconstruction in oral and oropharyngeal reconstruction: a systematic review[J]. Head Neck, 2016, 38(11): 1717-1721.
[5] Miloro M, Ruckman P 3rd, Kolokythas A. Lingual nerve repair: to graft or not to graft?[J]. J Oral Maxillofac Surg, 2015, 73(9): 1844-1850.
[6] Zuniga JR.Sensory outcomes after reconstruction of lingual and inferior alveolar nerve discontinuities using processed nerve allograft--a case series[J]. J Oral Maxillofac Surg, 2015, 73(4): 734-744.
[7] Erakat MS, Chuang SK, Shanti RM, et al.Interval between injury and lingual nerve repair as a prognostic factor for success using type I collagen conduit[J]. J Oral Maxillofac Surg, 2013, 71(5): 833-838.
[8] Van Der Cruyssen F, Van Tieghem L, Croonenborghs TM, et al. Orofacial quantitative sensory testing: current evidence and future perspectives[J]. Eur J Pain, 2020, 24(8): 1425-1439.
[9] Rolke R, Magerl W, Campbell KA, et al.Quantitative sensory testing: a comprehensive protocol for clinical trials[J]. Eur J Pain, 2006, 10(1): 77-88.
[10] Yekta SS, Smeets R, Stein JM, et al.Assessment of trigeminal nerve functions by quantitative sensory testing in patients and healthy volunteers[J]. J Oral Maxillofac Surg, 2010, 68(10): 2437-2451.
[11] Renton T, Thexton A, Crean SJ, et al.Simplifying the assessment of the recovery from surgical injury to the lingual nerve[J]. Br Dent J, 2006, 200(10): 569-573.
[12] Kogan M, Lee KC, Chuang SK, et al.Outcomes of direct lingual nerve repair after an injury: a systematic review[J]. J Oral Maxillofac Surg, 2021, 79(3): 697-703.
[13] Svensson P, Baad-Hansen L, Pigg M, et al.Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions-a taskforce report[J]. J Oral Rehabil, 2011, 38(5): 366-394.
[14] Agbaje J, De Laat A, Constantinus P, et al.Agreement between quantitative and qualitative sensory testing of changes in oro-facial somatosensory sensitivity[J]. J Oral Rehabil, 2017, 44(1): 30-42.
[15] Ziccardi VB, Dragoo J, Eliav E, et al.Comparison of current perception threshold electrical testing to clinical sensory testing for lingual nerve injuries[J]. J Oral Maxillofac Surg, 2012, 70(2): 289-294.
[16] Hashmi JT, Huang YY, Osmani BZ, et al.Role of low-level laser therapy in neurorehabilitation[J]. PM R, 2010, 2(12 Suppl 2): S292-S305.
[17] Liu Z, Wang H, Yu T, et al.A review on the mechanism of Tuina promoting the recovery of peripheral nerve injury[J]. Evid Based Complement Alternat Med, 2021: 6652099.
[18] Paez-Hurtado A, Calderon-Ospina C, Nava-Mesa MO.Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review[J]. Nutr Neurosci, 2022: 1-19.
[19] Sawangjit R, Thongphui S, Chaichompu W, et al.Efficacy and safety of mecobalamin on peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials[J]. J Altern Complement Med, 2020, 26(12): 1117-1129.
[20] 武建康, 张卫东. 中药复方制剂治疗周围神经损伤的临床疗效观察[J]. 中华手外科杂志, 2010, 26(5): 317-318.
Wu JK, Zhang WD.Clinical effect of Chinese herbal compound preparation on peripheral nerve injury[J]. Chinses Journal of Hand Surgery, 2010, 26(5): 317-318.
[21] Romsa B, Ruggiero SL.Diagnosis and management of lingual nerve injuries[J]. Oral Maxillofac Surg Clin North Am, 2021, 33(2): 239-248.
[22] Bagheri SC, Meyer RA, Khan HA, et al.Retrospective review of microsurgical repair of 222 lingual nerve injuries[J]. J Oral Maxillofac Surg, 2010, 68(4): 715-723.
[23] Romsa B, Ruggiero SL.Diagnosis and management of lingual nerve injuries[J]. Oral Maxillofac Surg Clin North Am, 2021, 33(2): 239-248.

口腔癌患者术后舌神经功能障碍与生活质量的关系评价

Relationship between postoperative lingual nerve dysfunction and quality of life in oral cancer patients

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