Progress of botulinum toxin type A in the treatment of non-neoplastic salivary gland disease

doi:10.19438/j.cjoms.2022.06.016

Abstract

Abstract: Botulinum toxin A (BTX-A) is a neurotoxic protein that inhibits the release of acetylcholine and blocks cholinergic receptor signaling. BTX-A therapy has been widely used in many fields. In recent years, the application value and indications of BTX-A have been continuously explored and expanded, and more and more studies have focused on its application in the treatment of salivary gland-related diseases, such as sialorrhea, salivary fistula, salivary gland cyst, Frey's syndrome et al. In this paper, the literature on the use of BTX-A in the treatment of non-neoplastic salivary gland diseases including chronic obstructive parotitis in recent years was reviewed, and the treatment dosage, injection method and treatment effect were summarized and discussed, in order to provide reference and guidance for the clinical application in the treatment of chronic obstructive parotitis, sialorrhea and salivary fistula.

Key words: Chronic obstructive parotitis, Botulinum toxin A, Sialorrhea, Salivary fistula

CLC Number:

R781.7

HUANG Jian-hu, ZHAO Heng-shuai, WEI Jiang-ping. Progress of botulinum toxin type A in the treatment of non-neoplastic salivary gland disease[J]. China Journal of Oral and Maxillofacial Surgery, 2022, 20(6): 607-611.

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