Abstract: PURPOSE: To compare the application value of modified early warning score (MEWS) and corrected MEWS in patients with descending necrotizing mediastinitis. METHODS: A retrospective analysis of the clinical data of 65 patients with descending necrotizing mediastinitis treated from July 2018 to December 2019 was performed, and whether the patient developed severe disease was used as the observation index. The patients were evaluated with MEWS and corrected MEWS respectively, and the sensitivity and specificity of the two scoring methods to assess the severity of disease and prognosis were compared. SPSS 22.0 software package was used for statistical analysis. RESULTS: Both scoring scales had a moderate degree of resolution in predicting the severity of the patient's disease, the corrected MEWS score was significantly higher than the MEWS score (Z=2.257, P=0.024), the area under the ROC curve of MEWS was 0.669 (95% CI: 0.538-0.800, P=0.023), and the area under the ROC curve of the corrected MEWS was 0.818 (95% CI: 0.718-0.917, P=0.000). CONCLUSIONS: The corrected MEWS scoring can more effectively reflect the severity of the patient's condition at the time of admission, which is helpful for nurses to find out the potential disease risk of patients in the early stage, do a good job in emergency treatment in time, thus having important clinical significance for improving the safety of patients' medical care.

Key words: Descending necrotizing mediastinitis, Modified early warning score, Corrected modified early warning score, Early warning score value