Analysis of long-term prognosis for 172 cases undergoing mandibular reconstruction with free fibular flap

doi:10.19438/j.cjoms.2019.04.011

China Journal of Oral and Maxillofacial Surgery ›› 2019, Vol. 17 ›› Issue (4): 337-341.doi: 10.19438/j.cjoms.2019.04.011

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Analysis of long-term prognosis for 172 cases undergoing mandibular reconstruction with free fibular flap

WANG Jian¹, HE You-ya², CHEN Yi-ming², YANG Xi², JI Tong²

1.Department of Oromaxillofacial Head and Neck Oncology, Fengxian Hospital of Fengxian District, Shanghai Ninth People's Hospital Group. Shanghai 200011;
2. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University Shool of Medicine; National Clinical Research Center for Oral Disease; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011, China;

Received:2019-01-03 Revised:2019-03-28 Online:2019-07-20 Published:2019-08-12

Abstract

Abstract: PURPOSE: To analyze the clinical features and risk factors of late complications for patients who received mandibular reconstruction with free fibular flap. Methods: A retrospective study of patients undergoing mandibular reconstruction with free fibular flap from 2011 to 2013 in our hospital was reviewed. Demographic, clinical, imaging, pathological and follow-up data were collected and analyzed with SPSS 17.0 software package. Results: Data of 172 patients were collected, 142 were followed up. Among 142 patients, 19 had late complications, which occurred at a median time of 8 months. Preoperative or postoperative radiotherapy (P=0.02), different type of Ti plates(P=0.019), and the disease characteristics(P=0.02) were significant factors on univariate analysis. Multivariate analysis showed that postoperative radiation(P=0.009) and smoking history (P=0.037) were independent significant factors for late complications. Secondary reconstruction(P=0.069) and preoperative radiotherapy(P=0.086) were potential significant risk factor. Conclusions: Postoperative radiation and smoking history are associated with late complications. Mini-Ti plate should be used cautiously. Patients with risk factors need to be observed for at least 6 to16 months before further management.

Key words: Free fibular flap, Late complications, Radiotherapy, Smoking history

CLC Number:

R739.8

WANG Jian, HE You-ya, CHEN Yi-ming, YANG Xi, JI Tong. Analysis of long-term prognosis for 172 cases undergoing mandibular reconstruction with free fibular flap[J]. China Journal of Oral and Maxillofacial Surgery, 2019, 17(4): 337-341.

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Analysis of long-term prognosis for 172 cases undergoing mandibular reconstruction with free fibular flap

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