China Journal of Oral and Maxillofacial Surgery ›› 2018, Vol. 16 ›› Issue (1): 84-88.doi: 10.19438/j.cjoms.2018.01.018

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Research progress of inflammatory myofibroblastic tumor in head and neck region

PENG Can-bang1, TIAN Zhen2, JI Tong1   

  1. 1.Department of Oromaxillofacial Head and Neck Oncology, 2.Department of Oral Pathology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology;; National Clinical Research Center of Stomatology. Shanghai 200011, China
  • Received:2017-05-10 Revised:2017-07-20 Online:2018-01-20 Published:2018-02-11

Abstract: Inflammatory myofibroblastic tumor (IMT) is a distinctive mesenchymal neoplasm, composed of myofibroblasts/ fibroblasts, plasma cells, lymphocytes and/or infiltrating eosinophils. It is not common in the head and neck region, which resulted in the lack of standards of treatment and prognosis for the disease. This paper reviewed the current literature on the etiology, clinical features, pathology, treatment and prognosis of IMT in order to facilitate better recognition and treatment of IMT in head and neck region.

Key words: Inflammatory myofibroblastic tumor, ALK, Cox-2 inhibitor

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