Efficacy of partial superficial parotidectomy versus superficial parotidectomy for benign neoplasm of superficial parotid gland: meta-analysis

Abstract

Abstract: PURPOSE: To systematically review the clinical effects and safety of partial superficial parotidectomy (PSP) and superficial parotidectomy (SP) for benign neoplasm of superficial parotid gland. METHODS: We searched PubMed, EMbase, The Cochrane Library (Issue 4, 2015), Web of Knowledge、CNKI、CBM、Wan Fang Data and VIP up to April 2015. Randomized controlled trials involving treatment outcomes of benign neoplasm of superficial parotid gland using partial superficial parotidectomy (PSP) compared with superficial parotidectomy (SP) were included.Two reviewers independently screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the methodological quality of the included studies. RevMan5.2 software was used for meta analysis. RESULTS: A total of 11 studies involving 809 patients were included. The results of meta analysis showed there were significant differences between PSP group and SP group in transient or permanent facial paresis [RR=0.41, 95%CI(0.23,0.72), P=0.002], salivary fistula or subcutaneous effusion [RR=0.32, 95%CI(0.16,0.64), P=0.001], Frey's syndrome [RR=0.38, 95%CI(0.26,0.55), P<0.0001], facial asymmetry or scar deformity [RR=0.19, 95%CI(0.12,0.31), P<0.0001], reduction of salivary flow or xerostomia [RR=0.04, 95%CI(0.02,0.09), P<0.0001]; occurrence of great auricular analgesia was significantly less in PSP group than SP group; there was no significant difference in tumor recurrence between the two groups [RR=0.98, 95%CI(0.34,2.86), P=0.98]. CONCLUSIONS: Compared with SP, PSP does not increase the recurrence rates. Meanwhile, compared with SP, PSP shows lower incidence of postoperative complications in transient or permanent facial paresis, salivary fistula or subcutaneous effusion, Frey’s syndrome, facial asymmetry or scar deformity, reduction of salivary flow or xerostomia, and great auricular analgesia.PSP is a safe and effective technique for treatment of benign neoplasm of superficial parotid gland with certain advantages over SP, which can be widely applied in clinic.

Key words: Parotid gland benign tumor, Partial superficial parotidectomy, Superficial parotidectomy, Systematic review, Meta analysis, Randomized controlled trial

CLC Number:

R781.7

LI Chen-xi, LIU Hui, GONG Zhong-cheng, LING Bin, KEREMU·Abasi, LIN Zhao-quan. Efficacy of partial superficial parotidectomy versus superficial parotidectomy for benign neoplasm of superficial parotid gland: meta-analysis[J]. China Journal of Oral and Maxillofacial Surgery, 2016, 14(3): 263-269.

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