摘要： It has been expected that chemotherapy, as one of the major modalities in the management of cancer, would exert some beneficial effects on head and neck tumors. However, most of the pathologic types of head and neck solid carcinoma are of squamous cell variety, which seems no long-term radical response to any regimens of chemotherapy so far，according to the literature reports since the advent of chemotherapy. It is suggested at present no chemotherapy be applied to head and neck cancer patients for the purpose of a radical cure, which could be brought about by surgery or radiotherapy. Some of the literature that advocated chemotherapy on head and neck cancer is unjustifiable, not without personal bias. Clinical investigation should be further conducted on a small scale and in a rigorous way at research units in order to find a curative and treatment advice for head and neck oncologists in future.