Top Read Articles

    Published in last 1 year |  In last 2 years |  In last 3 years |  All
    Please wait a minute...
    For Selected: Toggle Thumbnails
    Chinese Expert consensus on the diagnosis, treatment of odontogenic keratocyst
    LIU Bing, HE Yue, PENG Xin, SUN Chang-fu, HAN Zheng-xue, WU Yu-nong, PENG Li-wei, ZHAO Yi, TAO Qian, HAN Xin-guang, LI Jin-song, SU Tong, LI Bo, ZHANG Lei, HU Yan-ping, CHEN Chuan-jun, LI Yi, LI Tie-jun, ZHAO Yi-fang
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 209-218.   DOI: 10.19438/j.cjoms.2022.03.001
    Abstract1485)      PDF (1176KB)(588)      
    Odontogenic keratocyst (OKC) is a common cystic lesion of the jaw. The nomenclature and nature of OKC remain controversial as a result of its local invasive behavior and high tendency of recurrence, which is evidently different from other types of jaw cysts. With the in-depth study of OKC pathogenesis and the advance of treatment concept and surgical techniques, it becomes possible to reduce the rate of postoperative recurrence and simultaneous functional reconstruction of the jaw. To establish standard diagnosis and treatment algorithms or guidelines of OKC, we organized peer experts in China to reach a consensus on pathogenesis, clinical manifestations, imaging characteristics, histopathological features, surgery and postoperative follow-up strategies of OKC for the references of clinicians.
    Reference | Related Articles | Metrics
    Efficacy of I.lanceolatum injection on postoperative reaction following dental implant surgery
    ZHU Qing-qing, SUN Qiang, WANG Dong-ling, ZHOU Hong
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 230-234.   DOI: 10.19438/j.cjoms.2022.03.004
    Abstract1182)      PDF (607KB)(73)      
    PURPOSE: The aim of this study was to explore the effects of i.lanceolatum injection on postoperative reaction , following the placement of dental implants with guided bone regeneration(GBR). METHODS: Ninety patients requiring dental implants with GBR were included in this randomized controlled clinical trial. The patients were evenly divided into 3 groups. I.lanceolatum injection was adopted in the experimental group after surgery, dexamethasone injection was adopted in the control group, and patients didn't receive any injection in the blank group. Postoperative pain, swelling, early wound healing, and satisfaction were analyzed and evaluated after follow-up appointments at day 1, day 3, and day 7. SPSS 25.0 software package was used for data analysis. RESULTS: The experiment group had significantly lower pain and swelling indices than the blank group at day 1 and 3(P<0.05); it also had higher wound healing indices than the blank group at day 1 and 3(P<0.05). Operative satisfaction indices of the experimental and control group were significantly higher than the blank group(P<0.05). CONCLUSIONS: Postoperative adverse reactions can be improved by using i.lanceolatum injection following dental implant surgery with GBR.
    Reference | Related Articles | Metrics
    Mechanism of EGFR-targeted drugs for pain relief in oral cancer
    WEI Dong-liang, LI Zhi, JU Hou-yu, WU Yun-teng, GUO Wei, REN Guo-xin
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 219-224.   DOI: 10.19438/j.cjoms.2022.03.002
    Abstract1101)      PDF (907KB)(207)      
    PURPOSE: The purpose of this study was to investigate whether drugs targeting EGFR (erlotinib, Nimotuzumab) could affect the pain threshold of experimental animals and to preliminarily explore the mechanism. METHODS: Naive mice were divided into two groups(physiological saline, n=6; erlotinib, n=6), the difference of pain threshold between the two groups was compared by Von Frey fiber test, hot plate test and 5% formalin test 1 h after administration. Nude mice were selected and divided into 3 groups (Sham + NS group, n=10; Plantar neoplasia + NS group, n=10; Plantar neoplasia + Nimotuzumab group, n=10). The mechanical pain threshold and thermal pain threshold of the mice were detected 1d before modeling and 1, 5, 7, 10 and 14 d after modeling. The mouse feet were dissected 14 days later, and the concentrations of IL-1β and IL-6 were detected by ELISA after tissue homogenization. The data were processed by Graphpad Prism statistical software. RESULTS: After erlotinib injection, the mechanical pain threshold and thermal pain threshold of mice had no obvious changes. After injection of 5% formalin in mice, the duration of licking in the anterior phase (0-10 min, P<0.01) and posterior phase (10-60 min, P<0.01) decreased significantly. Heat and mechanical pain sensitivity could be induced after plantar tumor formation in nude mice. Nimotuzumab slowed down tumor growth rate and increased thermal pain threshold (P<0.05) and mechanical pain threshold (P<0.05) in plantar tumorigenic mice. ELISA showed that the concentration of IL-1β (P<0.05) and IL-6 (P<0.05) in the plantar tissue of mice in the Nimotuzumab treatment group was significantly lower than that of the PBS treatment group. CONCLUSIONS: Erlotinib can alleviate pain induced by formalin in mice. Nimotuzumab can reduce mechanical and thermal pain sensitivity induced by plantar tumor formation, and the mechanism may be related to the decrease of inflammatory cytokines in local tissues. EGFR-targeted drugs may be one of the good analgesics for patients with advanced cancer pain.
    Reference | Related Articles | Metrics
    Neoadjuvant immunotarget therapy in patients with locally advanced oral squamous cell carcinoma: report of 2 cases and literature review
    ZHANG Yi-yi, YANG Yue-yi, JU Wu-tong, ZHONG Lai-ping
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (4): 413-416.   DOI: 10.19438/j.cjoms.2022.04.018
    Abstract893)      PDF (938KB)(78)      
    Neoadjuvant therapy is systemic therapy before local treatment in patients with non-distant metastatic malignancies, aiming to reduce tumor load and distant metastasis, increase opportunity of radical resection, and relieve symptoms, et al. In this report, we presented two patients with locally advanced oral squamous cell carcinoma, who were treated with camrelizumab and apatinib as neoadjuvant therapy in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, and reviewed and discussed the relevant literatures.
    Reference | Related Articles | Metrics
    Chinese experts consensus on the use of oral propranolol for treatment of infantile hemangiomas(version 2022)
    ZHENG Jia-wei, WANG Xu-kai, QIN Zhong-ping, FAN Xin-dong, LI Kai, YANG Yao-wu, HUO Ran, LIU Shao-hua, ZHAO Ji-hong, WANG Xiao-yong, ZHOU De-kai, LIU Xue-jian
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (4): 313-319.   DOI: 10.19438/j.cjoms.2022.04.001
    Abstract766)      PDF (1061KB)(592)      
    Since 2008, propranolol has become the first-line treatment for infantile hemangiomas. Many researches have been reported on its treatment mechanism both at home and abroad, and several expert consensus or clinical practice guidelines have been formulated and published. In recent years, with the continuous accumulation of clinical experience, increasing number of basic research works, and deepening understanding of the pathogenesis of hemangioma and the mechanism of action of propranolol, it is necessary to update the expert consensus to be more consistent with clinical practice, in order to guide medication and management, provide scientific norms for the clinical use of propranolol in the treatment of infantile hemangiomas. This updated version mainly simplified the process of clinical examination, medication, and monitoring, making it more convenient and operable.
    Reference | Related Articles | Metrics
    Comparison of the effect of two kinds of biopsy on prognosis of oral mucosal malignant melanoma - a retrospective analysis of156cases
    HAN Ru-xue, MA Xu-hui, LI Zhi, REN Guo-xin, GUO-Wei, WU Yun-teng, LIANG Xiang
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 235-238.   DOI: 10.19438/j.cjoms.2022.03.005
    Abstract612)      PDF (682KB)(83)      
    PURPOSE: To compare the effect of two kinds of biopsy on prognosis of oral mucosal malignant melanoma (OMM), in order to find an optional biopsy method for OMM. METHODS: Patients with OMM treated at Shanghai Ninth Hospital, Shanghai Jiao Tong University School of Medicine from Jan.2010 to Jan.2018 were retrospectively analyzed. Correlation between biopsy methods and prognosis were explored. Overall survival (OS) was the primary outcome, and OS was the time from pathological diagnosis to the date of death or follow-up (September 1, 2021). SAS 9.3 software was used for statistical analysis. RESULTS: Univariate analysis showed that T stage, cervical lymph node(CLN) status, biopsy type and OS were statistically correlated. All the three variables were included in Cox regression model for multivariate analysis. The results showed that T stage, CLN and biopsy type were independent prognostic factors of OS(P<0.05). CLN and biopsy methods were identified as prognostic factors. Incidences of CLN and distant metastasis were both significantly less in cryogenic biopsy group than in incisional biopsy group (53% vs. 74% and 22% vs. 42%, Log-rank=12.955, P<0.01 respectively). The 3- and 5-year OS was significantly longer in cryogenic biopsy group than in incisional biopsy group (65% vs. 42%,Log-rank=12.570, P<0.01 and 54% vs. 20%, Log-rank=7.203, P<0.01, respectively). CONCLUSIONS: The 3- and 5- year OS in cryogenic biopsy group was significantly better than that in the incisional biopsy group. Cryogenic biopsy could significantly reduce CLN and distant metastasis of OMM. Therefore, Use of cryogenic biopsy instead of incisional biopsy to clarify the diagnosis of OMM is recommended.
    Reference | Related Articles | Metrics
    Imaging features of temporomandibular joint disorder: comparison of the efficacy of cone-beam CT, MRI
    CHEN Jian-rong, DING Shui-qing, CHEN Liang, HE Jia-jia, QI Rong-xing
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 273-276.   DOI: 10.19438/j.cjoms.2022.03.012
    Abstract519)      PDF (460KB)(149)      
    PURPOSE: To analyze the features on cone-beam CT (CBCT) and MRI of temporomandibular joint disorder (TMD). METHODS: The data of 45 patients with TMD treated in Nantong Hospital of Stomatology from August 2018 to May 2020 were collected. All patients completed CBCT and MRI within 2 weeks, and the characteristics of TMJ and masticatory muscle lesions on CBCT and MRI were evaluated, including joint space stenosis, bone destruction, bone hyperplasia and sclerosis, condyle deformation, bone cystoid degeneration, articular disc displacement, joint capsule effusion and masticatory muscle lesions. SPSS 25.0 software package was used for data analysis. RESULTS: According to TMD clinical classification, 31 cases (68.9%) were classified as type I painful diseases, and 14 cases (31.1%) were classified as type II joint diseases. Among the 90 joints of 45 patients, the number of TMJ and masticatory muscle lesions detected by MRI (71/90) was significantly higher than the number of lesions detected by CBCT (58/90) (P=0.032). Among them, the number of articular disc displacement (19/90), joint capsule effusion (28/90) and masticatory muscle edema (22/90) were significantly higher than the number of cases detected by CBCT which was 3/90, 8/90 and 5/90 (P<0.001). The number of cases of hyperosteosis (18/90) and condyle mutation (15/90) detected by CBCT was significantly higher than the number of cases detected by MRI which was 8/90 and 6/90 (P<0.05). CBCT and MRI had no significant differences in detecting joint space stenosis, bone destruction and cystoid degeneration(P>0.05). CONCLUSIONS: Both CBCT and MRI have high clinical value in evaluating TMD. CBCT has advantages in evaluating bone quality, while MRI has a good effect in evaluating joint discs and soft tissues.
    Reference | Related Articles | Metrics
    Application and advancement of minimally invasive instruments and micro-power devices in tooth extraction
    LI Yan-xiang, YAN Li-jun, LING Xiao-wan, ZHOU Wen-jie, WANG Yue-ping
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 191-196.   DOI: 10.19438/j.cjoms.2023.02.016
    Abstract493)      PDF (914KB)(215)      
    Tooth extraction is to remove the affected teeth that can no longer provide oral function, and it is also one of the most basic and common procedures in alveolar surgery. Conventional tooth extraction applies elevators, forceps, chisels and other instruments, which may cause severe physical and psychological trauma to the patient. In recent years, the concepts of minimally invasive tooth extraction has been accepted in the clinic, and the development of materials has led to more refined extraction instruments. Meanwhile the use of micro-power devices has greatly improved the efficiency of tooth extraction. Advancements in tooth extraction techniques and equipments are aimed to maximumly preserve the integrity of the alveolar bone, reduce the complications, and relieve the pain. This paper described the development of minimally invasive tooth extraction techniques through the evolution of instruments and the application of micro-power devices, so as to provide reference for more dentists to understand and apply minimally invasive equipments in daily practice.
    Reference | Related Articles | Metrics
    Case report of parotid, submandibular lymph node metastasis of ocular sebaceous gland carcinoma
    FU Hong-hai, QIU Na-na, SUN Le-gang, WANG Fang
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 307-309.   DOI: 10.19438/j.cjoms.2022.03.019
    Abstract473)      PDF (894KB)(81)      
    Ocular sebaceous gland carcinoma usually occurs in the upper eyelid, and metastasis to the parotid gland and submandibular lymph node is rare. Therefore, it is necessary to differentiate it from the primary parotid gland tumor in clinical practice. In this paper, we reported a case of ocular sebaceous gland carcinoma of the upper eyelid with metastasis to the parotid and submandibular lymph nodes, providing clinical guidance for the diagnosis and treatment of this disease.
    Reference | Related Articles | Metrics
    Prognostic factors of primary intraosseous squamous cell carcinoma: a retrospective review of98consecutive cases
    YANG Jin-gang, XIA Rong-hui, ZHU Yun, WU Si-cheng, DONG Ya-bing, YANG Gong-xin, SHI Jun-long, CUI Ying-hui, ZHU Ling, ZHOU Shang-hui
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 239-243.   DOI: 10.19438/j.cjoms.2022.03.006
    Abstract472)      PDF (529KB)(144)      
    PURPOSE: To delineate the clinical and pathological features and determine the prognostic factors of primary intraosseous squamous cell carcinoma (PIOSCC). METHODS: The clinical, radiological, histopathological and postoperative follow-up data of patients diagnosed with PIOSCC in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from 2013 to 2017 were collected, and the prognostic factors of PIOSCC were analyzed by descriptive statistical methods. Baseline data were analyzed by univariate and multivariate survival analysis with SPSS 23.0 software package. RESULTS: A total of 98 patients with PIOSCC were enrolled, with a mean age of 56.6 years. Among them, there were 71 males and 27 females, and 33 in the maxilla, 65 in the mandible. Of the 95 patients followed up, 24 patients developed local recurrences and 10 patients developed distant metastases; furthermore, most local recurrences and distant metastasis occurred within 2 years after operation. The estimated 2-year and 5-year overall survival were 74.7% and 61.8%, respectively. Univariate analysis showed that tumor site, tumor size, positive margin, and cervical lymph node metastasis were significant prognostic factors for overall survival; facial numbness, positive margin were significant prognostic factors for local recurrences; and tumor site, cervical lymph node metastasis were significant prognostic factors for distant metastasis. Multivariate analysis showed that only positive margin and cervical lymph node metastasis remained as significant prognostic factors for overall survival. CONCLUSIONS: Recurrence, metastasis, and death occurred most frequently within 2 years after operation of PIOSCC. Positive margin and cervical lymph node metastasis were negative prognostic factors for PIOSCC.
    Reference | Related Articles | Metrics
    Effect of columnar collagen sponge on the extraction of impacted teeth and the risk of complications
    WANG Chen-xin, PENG Jing, HUANG Xin, SHI Le, DAI Xiao-feng
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 146-151.   DOI: 10.19438/j.cjoms.2023.02.008
    Abstract427)      PDF (963KB)(129)      
    PURPOSE: To investigate the effect of collagen sponge in the extraction of impacted teeth and the risk of complications. METHODS: A total of 160 patients with impacted teeth extraction were selected from June 2021 to December 2021 in Shanghai Jing'an Dental Clinic. The patients were randomly divided into experimental group and control group, 80 cases in each group. Both groups underwent conventional extraction of impacted teeth, and the control group was rinsed with 20 mL sodium chloride solution after extraction. In the experimental group, on the basis of the control group, columnar collagen sponge was inserted into the extraction wound. Bleeding, postoperative pain score, postoperative swelling degree 7 days after surgery, levels of inflammatory factors[prostaglandin E2(PGE2), myeloperoxidase(MPO), calcitonin gene-related peptide(CGRP)] in gingival crevicular fluid before and after treatment and postoperative complications (restricted opening, inflammatory induration or bruising of maxillofacial region, infection, dry socket) were compared between the two groups. SPSS 22.0 software package was used for data analysis. RESULTS: The postoperative bleeding time of the experimental group was significantly lower than that of the control group(P<0.05). The VAS scores of spontaneous pain and dysphagia in the experimental group were significantly lower than those of the control group(P<0.05). The swelling degree of experimental group was significantly lower than that of control group 7 days after tooth extraction(P<0.05). There was no difference in PGE2, MPO and CGRP between the two groups before treatment(P>0.05). After treatment, PGE2, MPO and CGRP in the two groups were significantly increased(P<0.05), PGE2, MPO and CGRP of the experimental group after treatment were significantly lower than those of the control group after treatment(P<0.05). The incidence of postoperative complications in the experimental group was significantly lower than that in the control group (P<0.05). CONCLUSIONS: Columnar collagen sponge has a good effect in extraction of impacted teeth, and can effectively avoid postoperative complications, and has little influence on inflammatory factors in gingival crevicular fluid, which is worthy of wide application.
    Reference | Related Articles | Metrics
    Construction and in vitro evaluation of an injectable multifunctional liposome-hydrogel composite for jaw defect repair
    XUN Xing-xiang, SUN Wei, WANG He-jing, CHU Chen, ZHAO Qian, XU Xiao, YUAN Rong-tao
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (6): 534-540.   DOI: 10.19438/j.cjoms.2022.06.003
    Abstract424)      PDF (1217KB)(71)      
    PURPOSE: Liposome was used as a sustained release carrier for pro-vascularization small molecule desferrioxamine (DFO) and osteogenesis-inducing small molecule dexamethasone (Dex), while sodium alginate hydrogel was used as a sustained release carrier for vancomycin (Van) to construct an injectable liposome-hydrogel complex with simultaneous antibacterial, pro-angiogenic and osteogenic effects, and to investigate the ability of the complex to promote bone tissue regeneration and repair. METHODS: DFO/Dex liposomes were prepared by thin film dispersion method, and mixed with Van sodium alginate solution to form Van/DFO/Dex liposome-hydrogel complex under the action of calcium ions. The particle size, polydispersity index(PDI) and Zeta potential of the liposomes were measured by Zeta particle size analyzer. The sustained release curves of Van, DFO and Dex in the complex were determined by UV-vis spectrophotometer. Wst-8 quantitative assay was used to evaluate the antibacterial activity of the complex in vitro. CCK-8 and cell live/dead fluorescence staining were used to evaluate the cytocompatibility of the complex. Real-time fluorescence quantitative PCR (RT-PCR) was used to detect the angiogenesis promoting effect of the complex. ALP activity quantification and staining were used to evaluate the effect of Van/DFO/Dex liposome-hydrogel complex on promoting bone differentiation in vitro. OriginPro software was used for analysis of the data. RESULTS: An injectable Van/DFO/Dex liposome-hydrogel complex was successfully constructed. The particle size of the liposome was (121.6±6.35)nm, PDI was 0.2-0.3. The encapsulation rate of DFO was about 57% and that of Dex was about 23%. Sustained release curve showed that Van DFO and Dex were released continuously in stages. CCK-8 and cell live/dead fluorescence staining showed that Van/DFO/Dex liposome-hydrogel complex had good cytocompatibility. Quantitative detection of WST-8 showed that the complex had good antibacterial activity in vitro. The expression of genes related to angiogenesis suggests that the complex had the ability to promote angiogenesis. ALP activity quantification and staining showed that Van/DFO/Dex liposome-hydrogel complex could enhance osteogenic differentiation activity. CONCLUSIONS: Van/DFO/Dex liposome-hydrogel complex is a multifunctional bone regeneration material with osteogenesis, angiogenesis promotion and anti-infection, and its injectable properties are beneficial to the clinical application of irregular jaw defects.
    Reference | Related Articles | Metrics
    Comparison of reliability of 5 evaluation methods for intraoral tonsil hypertrophy in awake and anesthetized individuals
    YAO Kan, XIE Yi-lun, YU Wen-wen, WEI Si-long, XIA Liang, ZHENG Tong, LU Xiao-feng
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (5): 461-465.   DOI: 10.19438/j.cjoms.2022.05.008
    Abstract423)      PDF (861KB)(107)      
    PURPOSE: To determine the reliability of the 5 clinical grading scales of tonsillar size in reporting the size of tonsils in awake and anesthetized individuals. METHODS: Awake and anesthetized tonsillar images of 218 patients aged 3 to 14 years with no severe craniofacial abnormalities were retrospectively collected. For each patient, five separate tonsil assessments were conducted by 3 experienced experts. Intraclass correlation coefficients(ICC) and Cronbach's α were used to determine the reliability of tonsil size in awake and anesthetized state. Statistical analysis was performed with R language (version 3.6.3). RESULTS: The reliability was highest for traditional 3-grade scale (ICC, 0.58; Cronbach's α, 0.74), followed by Friedman grading scale (ICC, 0.57; Cronbach's α, 0.73), modified 3-grade scale (ICC, 0.57; Cronbach's α, 0.72), modified 5-grade scale(ICC, 0.42; Cronbach's α, 0.59) and Brodsky grading scale(ICC, 0.30; Cronbach's α, 0.46). CONCLUSIONS: The tonsils tended to be underestimated when the individuals were awake, while the 5 tonsil assessments were able to figure out the real volume of tonsils respectively.
    Reference | Related Articles | Metrics
    Symmetry analysis of short-term lip peak height after unilateral cleft lip repair with modified Onizuka method
    CHI Hao-shu, ZHAN Zong-li, ZHAO Zhi-yang, CAI Ming
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (6): 560-564.   DOI: 10.19438/j.cjoms.2022.06.007
    Abstract405)      PDF (837KB)(30)      
    PURPOSE: To explore the surgical technique of modified Onizuka cheiloplasty for the changes of bilateral lip peak heights and evaluate the postoperative symmetry in a short time. METHODS: Charts of 19 unilateral cleft lip patients who were repaired by modified Onizuka in Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine from September 2021 to December 2021 were retrospectively reviewed. The differences of bilateral lip peak heights immediately and one month after surgery and the changes of upper lip morphology were analyzed. The distance was measured by Adobe Photoshop CC software through photos. SPSS 25.0 software package was used for data analysis. RESULTS: The difference of lip peak height between the healthy side and the affected side was (0.40±0.35) mm and (0.53±0.40) mm immediately and 1 month after operation, respectively, there was no significant difference(P>0.05). It was found that the cupid’s bow was rebuilt in a natural form and the configuration of the upper lip was reconstructed symmetrically. The philtrum column was not disturbed by the small triangle flap. CONSLUSIONS: Modified Onizuka is an effective way for repairing unilateral cleft lip.
    Reference | Related Articles | Metrics
    Expert consensus on diagnosis and clinical management of medication-related osteonecrosis of the jaw
    HE Yue, CHEN Heng, AN Jin-gang, GUO Yu-xing, PAN Jian, TIAN Lei, LIU Bing, HOU Jin-song, LI Jin-song, JIANG Can-hua, LI Meng-yu, TIAN Zhen, XU Jie, ZHU Ling, SUN Chang-fu, ZHI Ke-qian, QU Qing, ZONG Chun-lin, SUN Jing-jing, ZHANG Zhi-yuan
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (4): 313-325.   DOI: 10.19438/j.cjoms.2023.04.001
    Abstract391)      PDF (2051KB)(512)      
    Medication-related osteonecrosis of the jaw(MRONJ) is a complication caused by the application of anti-resorptive medications, angiogenesis inhibitors, hormones and other medications for the treatment of some systemic diseases. The clinical symptoms include swelling, pain, masticatory disorders, persistent fistula, bone exposure and even pathological fracture, which seriously affect the patients' quality of life. Domestically, there is a lack of consensus or guidelines on classification, staging and treatment of MRONJ, and different institutions make diagnosis and treatment plans empirically. In order to unify and standardize the diagnosis and treatment of MRONJ and improve the prognosis, an expert panel of MRONJ research from 12 famous domestic medical colleges and affiliated hospitals convened a meeting to discuss the diagnosis and treatment opinions of MRONJ. Meanwhile, consensus recommendations were also revised with a comprehensive literature review of the previous treatment experiences and research findings. Finally, this expert consensus was finished for clinical references.
    Reference | Related Articles | Metrics
    Ultrasonography diagnosis of vascular tumors of the head and neck
    GONG Xia, LI Jia, XIONG Ping, DING Ang-ang
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (6): 521-526.   DOI: 10.19438/j.cjoms.2022.06.001
    Abstract382)      PDF (2118KB)(83)      
    Ultrasound is a non-invasive and convenient tool for diagnosis of vascular tumors of the head and neck, preoperative evaluation and follow-up of disease changes. Ultrasound technologies include grayscale imaging, color Doppler imaging, three dimensional color Doppler and elastography. This article summarized the ultrasound examination methods of these lesions based on the new classification of vascular lesions proposed by International Society for the Study of Vascular Anomalies(ISSVA), and reviewed the relevant clinical and ultrasound features including infantile and congenital hemangioma, pyogenic granuloma, tufted angioma and Kaposiform hemangioendothelioma, in order to provide an effective basis for clinical diagnosis and treatment.
    Reference | Related Articles | Metrics
    Tongue base tumor, open surgery or transoral robotic surgery?
    XI Qing
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (6): 527-533.   DOI: 10.19438/j.cjoms.2022.06.002
    Abstract378)      PDF (1307KB)(179)      
    Tongue base tumors are common in oral and maxillofacial surgery. The anatomical location of tongue base tumor is deep and difficult to treat, there is no consensus on the choice of surgical treatment. This article aimed to summarize the research progress in tongue base tumors, analyze and compare the treatment methods, summarize their advantages and disadvantages, and provide reference for clinical diagnosis and treatment of tongue base tumors.
    Reference | Related Articles | Metrics
    Progress on diagnosis and treatment of HPV-related oropharyngeal cancer
    WU Ya-ping, GAO Jia-min, SUN Shu-yang
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (6): 599-606.   DOI: 10.19438/j.cjoms.2022.06.015
    Abstract375)      PDF (807KB)(153)      
    The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been on the rise in recent years, and HPV infection is a critical risk factor for the occurrence of OPSCC. Due to its unique biological characteristics, sensitivity to chemoradiotherapy and good prognosis, HPV-related OPSCC has been classified as an independent disease in the 2017 AJCC and WHO staging system. However, there is no obvious difference in the clinical treatment of patients with HPV-related or non-related OPSCC. Therefore, search for a more suitable treatment plan for patients with HPV-related OPSCC has become a hot spot of current concern. This article reviewed the recent advances in the diagnosis and treatment of HPV-related OPSCC.
    Reference | Related Articles | Metrics
    Long-term effectiveness of periodontal micro-osteotomy assisted orthodontic treatment in adult patients with primary alveolar defect
    WANG Bo, YU Hong-bo, XIA Yun-yui, FANG Bing, GUO Qiu-man
    China Journal of Oral and Maxillofacial Surgery    2022, 20 (3): 225-229.   DOI: 10.19438/j.cjoms.2022.03.003
    Abstract374)      PDF (967KB)(117)      
    PURPOSE: To quantitively investigate the long-term effectiveness of periodontal micro-osteotomy assisted orthodontic treatment of adult patients with primary alveolar defect. METHODS: The sample consisted of 30 adult cases with primary alveolar defect in the lower anterior region who accepted periodontal micro-osteotomy assisted orthodontic treatment with over 2 years of follow-up, selected from consecutive patients at the Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital since Jan.2014. Alveolar bone morphology of lower anterior teeth with primary alveolar defect was appraised with the help of cone-beam CT (CBCT) in the surgical sites at different time points. The data were processed using SAS 9.1 software package. RESULTS: Periodontal micro-osteotomy assisted orthodontic treatment in adult patients with primary alveolar defect showed stable long-term effect of bone augmentation and minimal root resorption. However, the effect of bone augmentation was less when approaching the alveolar bone crest, and vertical alveolar bone loss was observed on both labial and lingual side in the surgical sites. CONCLUSIONS: Periodontal micro-osteotomy assisted orthodontic treatment is a promising approach for the treatment of adult patients with primary and inflammatory alveolar defect; however, vertical alveolar bone loss could be observed in the surgical sites.
    Reference | Related Articles | Metrics
    Using computerized tomography sialography in the diagnosis of parotid diseases
    GAO An-tian, LIANG Yi, LIN Zi-tong
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 158-162.   DOI: 10.19438/j.cjoms.2023.02.010
    Abstract372)      PDF (1400KB)(87)      
    PURPOSE: To investigate the key points of technique of computerized tomography sialography (CT-sialography) and its diagnostic value in parotid gland diseases. METHODS: A total of 34 patients with chronic parotitis, Sjogren's syndrome, parotid fistula and parotid tumors and tumor-like lesions were collected. All patients were scanned with spiral CT immediately after iodine contrast injection into the primary parotid duct, followed by image post-processing and disease diagnosis. The diagnostic accuracy was calculated according to the follow-up results and postoperative pathological results. The imaging characteristics of parotid gland diseases were summarized and analyzed. RESULTS: The overall diagnostic accuracy rate was 82.35%. The diagnostic accuracy rate of benign and malignant parotid tumors and tumor-like lesions was 88.24%. CONCLUSIONS: CT-sialography is an effective method for diagnosis of obstructive parotitis, parotid fistula, Sjogren's syndrome and tumor and tumor-like lesions in parotid gland.
    Reference | Related Articles | Metrics