%A ZHANG Yi-yi, YANG Yue-yi, JU Wu-tong, ZHONG Lai-ping %T Neoadjuvant immunotarget therapy in patients with locally advanced oral squamous cell carcinoma: report of 2 cases and literature review %0 Journal Article %D 2022 %J China Journal of Oral and Maxillofacial Surgery %R 10.19438/j.cjoms.2022.04.018 %P 413-416 %V 20 %N 4 %U {https://www.cjoms.org/CN/abstract/article_8440.shtml} %8 2022-07-20 %X Neoadjuvant therapy is systemic therapy before local treatment in patients with non-distant metastatic malignancies, aiming to reduce tumor load and distant metastasis, increase opportunity of radical resection, and relieve symptoms, et al. In this report, we presented two patients with locally advanced oral squamous cell carcinoma, who were treated with camrelizumab and apatinib as neoadjuvant therapy in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, and reviewed and discussed the relevant literatures.