Efficacy of I.lanceolatum injection on postoperative reaction following dental implant surgery

doi:10.19438/j.cjoms.2022.03.004

Abstract

Abstract: PURPOSE: The aim of this study was to explore the effects of i.lanceolatum injection on postoperative reaction , following the placement of dental implants with guided bone regeneration(GBR). METHODS: Ninety patients requiring dental implants with GBR were included in this randomized controlled clinical trial. The patients were evenly divided into 3 groups. I.lanceolatum injection was adopted in the experimental group after surgery, dexamethasone injection was adopted in the control group, and patients didn't receive any injection in the blank group. Postoperative pain, swelling, early wound healing, and satisfaction were analyzed and evaluated after follow-up appointments at day 1, day 3, and day 7. SPSS 25.0 software package was used for data analysis. RESULTS: The experiment group had significantly lower pain and swelling indices than the blank group at day 1 and 3(P<0.05); it also had higher wound healing indices than the blank group at day 1 and 3(P<0.05). Operative satisfaction indices of the experimental and control group were significantly higher than the blank group(P<0.05). CONCLUSIONS: Postoperative adverse reactions can be improved by using i.lanceolatum injection following dental implant surgery with GBR.

Key words: I.lanceolatum injection, Guided bone regeneration, Postoperative pain, Swelling, Dental implant

CLC Number:

R782.1

ZHU Qing-qing, SUN Qiang, WANG Dong-ling, ZHOU Hong. Efficacy of I.lanceolatum injection on postoperative reaction following dental implant surgery[J]. China Journal of Oral and Maxillofacial Surgery, 2022, 20(3): 230-234.

References

[1] Brånemark PI.Osseointegration and its experimental background[J]. J Prosthet Dent, 1983, 50(3): 399-410.
[2] Terheyden H.Bone augmentation in implantology[J]. Dtsch Zahnarztl Z, 2010, 65: 320-331.
[3] Chiapasco M, Zaniboni M.Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review[J]. Clin Oral Implants Res, 2009, 20(Suppl 4): 113-123.
[4] Sánchez-Siles M, Torres-Diez LC, Camacho-Alonso F, et al.High volume local anesthesia as a postoperative factor of pain and swelling in dental implants[J]. Clin Implant Dent Relat Res, 2014, 16(3): 429-434.
[5] Silveira ER, Cademartori MG, Schuch HS, et al.Estimated prevalence of dental fear in adults: a systematic review and meta-analysis[J]. J Dent, 2021, 108: 103632.
[6] 李媛媛. 红茴香注射液肌肉注射治疗软组织损伤129例[J]. 浙江中医杂志, 2012, 47(10): 746-750.
Li YY.129 cases of soft tissue injury treated with intramuscular injection of red fennel[J]. Zhejiang Journal of Traditional Chinese Medicine, 2012, 47(10): 746-750.
[7] 吴章振. 红茴香、复方当归注射液治疗多种伤痛的体会[J]. 吉林医学, 2012, 33(18): 3868-3868.
Wu ZZ.Experience of red fennel and compound angelica injection in the treatment of multiple injuries[J]. Jilin Medicine, 2012, 33(18): 3868-3868.
[8] 范兴达, 何冬梅. 红茴香及其活性成分治疗骨关节炎研究概况[J]. 中医药临床杂志, 2021, 33(10): 2019-2023.
Fan XD, He DM.Research progress of Illicium Henryi Diels and its active components in the treatment of osteoarthritis[J]. Journal of Clinical Chinese Medicine, 2021, 33(10): 2019-2023.
[9] Pereira GM, Cota LO, Lima RP, et al.Effect of preemptive analgesia with ibuprofen in the control of postoperative pain in dental implant surgeries: a randomized, triple-blind controlled clinical trial[J]. J Clin Exp Dent, 2020, 12(1): e71-e78.
[10] González-Santana H, Peñarrocha-Diago M, Guarinos-Carbó J, et al.Pain and inflammation in 41 patients following the placement of 131 dental implants[J]. Med Oral Patol Oral Cir Bucal, 2005, 10(3): 258-263.
[11] Erdogan Ö, Uçar Y, Tatli U, et al.A clinical prospective study on alveolar bone augmentation and dental implant success in patients with type 2 diabetes[J]. Clin Oral Implants Res, 2015, 26(11): 1267-1275.
[12] Buser D, Mericske-Stern R, Bernard JP, et al.Long-term evaluation of non-submerged ITI implants. Part 1: 8-year life table analysis of a prospective multi-center study with 2359 implants[J]. Clin Oral Implants Res, 1997, 8(3): 161-172.
[13] Nourwali I.The effects of platelet-rich fibrin on post-surgical complications following removal of impacted wisdom teeth: a pilot study[J]. J Taibah Univ Med Sci, 2021, 16(4): 521-528.
[14] Khouly I, Braun RS, Ordway M, et al.Post-operative pain management in dental implant surgery: a systematic review and meta-analysis of randomized clinical trials[J]. Clin Oral Investig, 2021, 25(5): 2511-2536.
[15] 侯亚丽, 李凤霞, 王庆华,等. 洛索洛芬钠不同给药时间对种植牙修复患者术后镇痛效果的影响[J]. 中国实用护理杂志, 2017, 33(19): 1455-1458.
Hou YL, Li FX, Wang QH, et al.Effect of postoperative analgesia with Loxoprofen sodium in different times on dental implant patients[J]. Chinese Journal of Practical Nursing, 2017, 33(19): 1455-1458.
[16] Al-Khabbaz AK, Griffin TJ, Al-Shammari KF.Assessment of pain associated with the surgical placement of dental implants[J]. J Periodontol, 2007, 78(2): 239-246.
[17] 陈坤利, 薛军. 地塞米松对口腔颌面部术后应激反应及炎症反应的影响[J].临床医学研究与实践, 2020, 5(14): 99-101.
Chen KL, Xue J.Effect of dexamethasone on stress and inflammation response after oral and maxillofacial surgery[J]. Clinical Medicine Research and Practice, 2020, 5(14): 99-101.
[18] Moeen SM, Ramadan IK, Elkady HA.Dexamethasone and dexmedetomidine as an adjuvant to intraarticular bupivacaine for postoperative pain relief in knee arthroscopic surgery: a randomized trial[J]. Pain Physician, 2017, 20(7): 671-680.
[19] Tang D, Kang R, Coyne CB, et al.PAMPs and DAMPs: signal 0s that spur autophagy and immunity[J]. Immunol Rev, 2012, 249(1): 158-175.
[20] 林祁. 八角属药用植物资源[J]. 中草药, 2002, 33(7): 654-657.
Lin Q.Medicinal plant resources of Illicium L[J]. Chinese Herbal Medicine, 2002, 33(7): 654-657.
[21] 龙全江, 杨韬. 芦丁的研究概况及展望[J]. 中国中医药信息杂志, 2002, 9(4): 39-42.
Long QJ, Yang T.General situation and prospect of research on Rutin[J]. Chinese Journal of Traditional Chinese Medicine Information, 2002, 9(4): 39-42.
[22] 马怡, 孙建宁, 徐秋萍, 等. 莽草酸对血小板聚集和凝血的抑制作用[J]. 药学学报, 2000, 35(1): 1-3.
Ma Y, Sun JN, Xu QP, et al.Inhibitory effects of shikimic acid on platelet aggregation and blood coagulation[J]. Journal of Pharmacology, 2000, 35(1): 1-3.