China Journal of Oral and Maxillofacial Surgery ›› 2021, Vol. 19 ›› Issue (5): 478-480.doi: 10.19438/j.cjoms.2021.05.018

• Case Reports • Previous Articles    

Fibromyxoid spindle cell tumor in the pterygopalatine fossa： a case report

SHI Fan1, XUE Ran2, ZHOU Xue-xiao1, SHEN Pei1, XU Ting3, WANG Sheng-zhi3   

  1. 1. School of Stomatology, Qingdao University. Qingdao 266003, Shandong Province;
    2. Department of Pharmacy, The First Affiliated Hospital of Xi 'an Jiaotong University, Chang'an District Hospital. Xi'an 710000, Shaanxi Province;
    3. Department of Oral and Maxillofacial Surgery, Affiliated Yantai Yuhuangding Hospital of Qingdao University. Yantai 264000, Shandong Province, China
  • Received:2021-03-10 Revised:2021-05-11 Online:2021-09-20 Published:2021-10-20

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Abstract: To report a rare case of fibromyxoid spindle cell tumor which occurred in the pterygopalatine fossa and discuss its imaging features, pathological diagnosis and treatment. A 58 years old female, CT showed nodular low-density mass in the right pterygopalatine fossa, enhanced CT showed mildly enhanced, with unclear boundaries, adjacent inferior wall of the right maxillary sinus was destructed, patchy enhanced shadow was seen in the posterior margin of the adjacent right maxilla and the right lateral muscle was oppressed. Spindle cell tumor of the right pterygopalatine fossa was confirmed under light microscopy. Morphological features were consistent with proliferative fibromas of bone connective tissue and mucous degeneration around the tumor. Immunohistochemistry showed that CK(-), S-100(-), AE1/AE3(-), SMA(-), CD34(-), Des(-), MUC-4(-), p63(-), STAT-6(-),β-catering (nuclear -), Dog1(-), the positive rate of Ki-67 was 2%.

Key words: Pterygopalatine fossa, Fibromyxoid spindle cell tumor, Operative approach

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