Abstract: PURPOSE: To summarize the experience of diagnosis and treatment of 56 oral cancer patients with systemic diseases. METHODS: The clinical data of 56 oral cancer patients with systemic diseases who were diagnosed and treated by Affiliated Hospital of Qingdao University were retrospectively reviewed. According to the features of oral cancer, the main therapy of primary tumor and systemic diseases were analyzed. RESULTS: In 56 patients, the treatment modalities for primary tumors included surgery, radiotherapy, chemotherapy, immunotherapy. Cardiovascular treatment was recommended for 34 patients (60.71%) with hypertension, 11 patients (19.64%) with coronary heart disease, 1 patient (1.79%) with severe arrhythmia. Twenty-three (41.07%) patients with diabetes mellitus were given reasonable blood sugar control protocol. Nineteen (33.93%) patients with respiratory diseases were given corresponding lung function test and treatment of complications after surgery. CONCLUSIONS: Multidisciplinary team approach is reasonable and effective for the diagnosis and therapy of oral cancer patients with systemic diseases, and it is worth of clinical application.

Key words: Oral cancer, Multidisciplinary team approach, Systemic disease