China Journal of Oral and Maxillofacial Surgery ›› 2019, Vol. 17 ›› Issue (1): 40-43.doi: 10.19438/j.cjoms.2019.01.007

• Original Articles • Previous Articles     Next Articles

A retrospective study of risk factors for life-threatening complications of multi-space infections of head and neck

HUANG Lin-jian1,2, CHEN Jun1, YAN Jun-lie1, XU Xin1, CAI Xie-yi2   

  1. 1. Department of Oral and Maxillofacial Surgery, The Second Affiliated Hospital, College of Medicine, Zhejiang University. Hangzhou 310009, Zhejiang Province;
    2. Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011, China;
  • Received:2018-08-01 Revised:2018-10-12 Online:2019-01-20 Published:2019-02-21

Abstract: PURPOSE: To assess the risk factors (age, gender, and underlying systemic diseases) of life-threatening complications of multi-space infections (LCMI) in the head and neck. METHODS: This was a retrospective cohort study that enrolled a sample of patients with multi-space infections who were referred from February 2006 through July 2014. The patients were classified into diabetic and nondiabetic group. Statistical analysis was performed using SPSS 19.0 software package. RESULTS: The highest incidence of LCMI was in 60-69 yr group (18.8%), which was significantly higher than 20-59 yr group (P=0.027). The correlation was further confirmed by multivariable analysis (odds ratio, 1.148; P=0.041). The odds of susceptibility for LCMI development in diabetic patients was 2.404 times as that of nondiabetic patients (odds ratio, 2.404; P=0.008). CONCLUSIONS: Aging and diabetes mellitus increase the risk of development of life-threatening complications in patients with multi-space infections of head and neck. To increase the chance of patient survival, we strongly recommended clinicians pay more attention to patients with multi-space infections, especially those over the age of 60 and/or diabetic patients.

Key words: Head and neck region, Space infection, Complications, Diabetes mellitus, Risk factor

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